Think (Gram) negative!

Benedikt Huttner; Stephan Harbarth

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Think (Gram) negative!

机译：认为（Gram）负面！

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The increasing prevalence of multiresistant Gram-negative bacteria of the Enterobacteriaceae family in Europe is a worrisome phenomenon. Extended spectrum betalactamase-producing Escherichia coli strains are widespread in the community and are frequently imported into the hospital. Of even more concern is the spread of carbapenem-resistant strains of Klebsiella spp. from regions where they are already endemic. Antibiotic use is a main driver of antibiotic resistance, which again increases broad spectrum antibiotic use, resulting in a vicious circle that is difficult to interrupt. The present commentary highlights important findings of a surveillance study of antimicrobial use and resistance in German ICUs over 8 years with a focus on Gram-negative resistance.

机译：在欧洲，肠杆菌科的多重耐药革兰氏阴性菌的流行正在增加。产生广谱β-内酰胺酶的大肠埃希氏菌菌株在社区中广泛分布，并经常输入医院。更令人担忧的是耐碳青霉烯的克雷伯菌属菌株的传播。来自已经流行的地区。抗生素的使用是抗生素抗药性的主要驱动力，这又增加了广谱抗生素的使用，从而导致难以打消的恶性循环。本评论重点介绍了对德国ICU进行8年以上抗菌药物使用和耐药性监测研究的重要发现，重点是革兰氏阴性耐药性。

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《Critical care :》 |2010年第3期|共页
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Benedikt Huttner; Stephan Harbarth;
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中图分类护理学;
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Think (Gram) negative!

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