Inhibition of Microorganisms by Topical Anesthetics

Jerome Kleinfeld; Philip P. Ellis

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Inhibition of Microorganisms by Topical Anesthetics

机译：局部麻醉药对微生物的抑制作用

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The effect of various topical anesthetics and their preservatives on the growth of Pseudomonas aeruginosa, Staphyloccoccus albus, and Candida albicans was investigated. The topical anesthetics were proparacaine HCl, tetracaine HCl, cocaine HCl, and benoxinate HCl. The preservatives were chlorobutanol and butyl p-hydroxybenzoate. Proparacaine inhibited C. albicans but not P. aeruginosa or S. albus. All three test organisms were inhibited to varying degrees by tetracaine, benoxinate, cocaine, chlorobutanol, and butyl p-hydroxybenzoate.

机译：研究了各种局部麻醉药及其防腐剂对铜绿假单胞菌，白葡萄球菌和白色念珠菌生长的影响。局部麻醉药是盐酸普罗卡因，盐酸丁卡因，盐酸可卡因和苯甲酸酯盐酸盐。防腐剂是氯丁醇和对羟基苯甲酸丁酯。普罗卡因可抑制白色念珠菌，但不能抑制铜绿假单胞菌或白bus。丁卡因，苯甲酸酯，可卡因，氯代丁醇和对羟基苯甲酸丁酯对三种测试生物均具有不同程度的抑制作用。

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《Applied Microbiology》 |1967年第6期|共3页
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Jerome Kleinfeld; Philip P. Ellis;
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中图分类微生物学;
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1. Non-centralized and functionally localized nervous system of ophiuroids: evidence from topical anesthetic experiments Non-centralized and functionally localized nervous system of ophiuroids: evidence from topical anesthetic experiments Non-centralized and functionally localized nervous system of ophiuroids: evidence from topical anesthetic experiments [J] . Yoshiya Matsuzaka, Eiki Sato, Takeshi Kano, Biology Open . 2017,第4期

机译：类风湿性关节炎的非集中和功能局部神经系统：局部麻醉实验的证据类风湿性关节炎的非集中和功能局部神经系统：局部麻醉实验的证据
2. Topical Anesthetics May Result in More Pain and Need for Rescue Anesthetics Than Infiltrative Anesthetics in Patients Undergoing Scaling and Root Planing (vol 148, pg 203, 2017) [J] . Brignardello-Petersen Romina The Journal of the American Dental Association . 2018,第2期

机译：局部麻醉剂可能导致患有更高的痛苦和需求而不是在进行缩放和根刨的患者中的渗透麻醉剂（Vol 148，PG 203,2017）
3. Topical anesthetics may result in more pain and need for rescue anesthetics than infiltrative anesthetics in patients undergoing scaling and root planing [J] . Romina Brignardello-Petersen The Journal of the American Dental Association . 2017,第12期

机译：局部麻醉剂可能导致更痛苦，并且需要救助麻醉剂而不是进行缩放和根部刨的患者渗透麻醉品
4. A residue in TM3 region of the NR1 subunit is critical for anesthetic inhibition of NMDA receptors [C] . M. Shiraishi, J. Ogata, JJ. Woodward, International Conference on Basic and Systemic Mechanisms of Anesthesia . 2005

机译：NR1亚基的TM3区中的残留物对于NMDA受体的麻醉抑制至关重要
5. Transformation of iron sulfide by oil field microorganisms and their inhibition by sulfur/polysulfide [D] . Lin, Shiping 2008

机译：油田微生物对硫化铁的转化及其对硫/多硫化物的抑制
6. Inhibition of Microorganisms by Topical Anesthetics [O] . Jerome Kleinfeld, Philip P. Ellis 1967

机译：局部麻醉药对微生物的抑制作用
7. Inhibition of Microorganisms by Topical Anesthetics [O] . Jerome Kleinfeld, Philip P. Ellis 1967

机译：局部麻醉剂抑制微生物
8. Isoform Specific Inhibition for Treatment of Pain and Reduction of Anesthetic Threshold. [R] . Tao, Y., Johns, R. A. 2005

机译：同种型特异性抑制治疗疼痛和减少麻醉阈值。

Inhibition of Microorganisms by Topical Anesthetics

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