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Increased Glucose Utilization in Corynebacterium glutamicum by Use of Maltose, and Its Application for the Improvement of l-Valine Productivity

机译:利用麦芽糖增加谷氨酸棒杆菌的葡萄糖利用及其在提高l-缬氨酸生产能力中的应用

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摘要

Corynebacterium glutamicum efficiently utilizes maltose as a substrate. We show here that the presence of maltose increases glucose utilization by raising the expression of ptsG , which encodes the glucose-specific EII permease of the phosphotransferase system. Consequently, the l-valine productivity of a pyruvate dehydrogenase complex-deficient C. glutamicum strain was improved by the presence of maltose.
机译:谷氨酸棒杆菌有效地利用麦芽糖作为底物。我们在这里显示,麦芽糖的存在通过提高ptsG的表达来增加葡萄糖的利用率,该表达编码磷酸转移酶系统的葡萄糖特异性EII渗透酶。因此,通过存在麦芽糖,可以提高丙酮酸脱氢酶复合物缺陷谷氨酸棒杆菌菌株的L-缬氨酸生产率。

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