Degradation of the Twin-Arginine Translocation Substrate YwbN by Extracytoplasmic Proteases of Bacillus subtilis

Laxmi Krishnappa; Carmine G. Monteferrante; Jan Maarten van Dijl

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Degradation of the Twin-Arginine Translocation Substrate YwbN by Extracytoplasmic Proteases of Bacillus subtilis

机译：枯草芽孢杆菌胞外蛋白酶降解双精氨酸易位底物YwbN

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Bacterial twin-arginine translocases can export fully folded proteins from the cytoplasm. Such proteins are usually resistant to proteolysis. Here we show that multiple extracellular proteases degrade the B. subtilis Tat substrate YwbN. This suggests either that secreted YwbN is not fully folded or that folded YwbN exposes protease cleavage sites.

机译：细菌双精氨酸转座酶可以从细胞质中输出完全折叠的蛋白质。这样的蛋白质通常对蛋白水解具有抗性。在这里，我们表明多种细胞外蛋白酶降解枯草芽孢杆菌Tat底物YwbN。这表明分泌的YwbN未完全折叠或折叠的YwbN暴露了蛋白酶切割位点。

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《Applied Microbiology》 |2012年第21期|共4页
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Laxmi Krishnappa; Carmine G. Monteferrante; Jan Maarten van Dijl;
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1. Degradation of the Twin-Arginine Translocation Substrate YwbN by Extracytoplasmic Proteases of Bacillus subtilis [J] . Laxmi Krishnappa, Carmine G. Monteferrante, Jan Maarten van Dijl Applied and Environmental Microbiology . 2012,第21期

机译：枯草芽孢杆菌胞外蛋白酶降解双精氨酸易位底物YwbN
2. The Twin-Arginine Signal Peptide of Bacillus subtilis YwbN Can Direct either Tat- or Sec-Dependent Secretion of Different Cargo Proteins: Secretion of Active Subtilisin via the B. subtilis Tat Pathway [J] . Marc A. B. Kolkman, René van der Ploeg, Michael Bertels, Applied and Environmental Microbiology . 2008,第24期

机译：枯草芽孢杆菌YwbN的双精氨酸信号肽可以指导Tat或Sec依赖性分泌不同的货物蛋白质：通过枯草芽孢杆菌Tat途径分泌活性枯草杆菌蛋白酶
3. The twin-arginine translocation (Tat) systems from Bacillus subtilis display a conserved mode of complex organization and similar substrate recognition requirements [J] . Barnett JP, van der Ploeg R, Eijlander RT, The FEBS journal . 2009,第1期

机译：枯草芽孢杆菌的双精氨酸易位（Tat）系统显示出复杂组织的保守模式和相似的底物识别要求
4. Construction of the Escherichia coli-Bacillus subtilis Shuttle Vector pBE2R and Identification of the Critical Residues Involved in the Autoprocessing of the Propeptide of the Alkaline Protease [C] . Run Wei, Xiao-mei Liang, Mei-juan Xuan, International conference on applied biotechnology . 2018

机译：大肠杆菌-枯草芽孢杆菌穿梭载体pBE2R的构建和鉴定涉及碱性蛋白酶前肽自加工的关键残基
5. Plant cell wall-degradation and twin-arginine translocation: Exploring Ralstonia solanacearum virulence factors. [D] . Gonzalez, Enid T. 2005

机译：植物细胞壁降解和双精氨酸易位：探索青枯雷尔氏菌毒力因子。
6. Degradation of the Twin-Arginine Translocation Substrate YwbN by Extracytoplasmic Proteases of Bacillus subtilis [O] . Laxmi Krishnappa, Carmine G. Monteferrante, Jan Maarten van Dijl 2012

机译：枯草芽孢杆菌胞质蛋白酶降解双精氨酸易位底物YwbN
7. Degradation of the Twin-Arginine Translocation Substrate YwbN by Extracytoplasmic Proteases of Bacillus subtilis [O] . Krishnappa, Laxmi, Monteferrante, Carmine G., van Dijl, Jan Maarten 2012

机译：枯草芽孢杆菌胞质蛋白酶降解双精氨酸易位底物YwbN
8. Proteolytic Processing of the Protease Which Initiates Degradation of Small, Acid-Soluble Proteins during Germination of Bacillus subtilis Spores [R] . Sanchez-Salas, J. L., Setlow, P. 1993

机译：蛋白酶的蛋白水解加工促进枯草芽孢杆菌孢子萌发过程中小酸性蛋白质的降解

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Degradation of the Twin-Arginine Translocation Substrate YwbN by Extracytoplasmic Proteases of Bacillus subtilis

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