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Method for Accelerated Identification of Arboviruses After Inoculation of Mice

机译:小鼠接种后虫媒病毒的快速鉴定方法

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Sequential titration of infective virus and complement-fixing antigen in brain and liver of suckling mice infected with the following virus strains—Dugbe (a new arbovirus), Congo (related to Crimean hemorrhagic fever virus), yellow fever, dengue 1 and dengue 2—showed a progressive increase in titer after infection. High titers of both infective virus and complement-fixing antigen were demonstrated long before the mice showed clinical signs of infection. It is suggested that earlier isolation and identification of arboviruses from clinical and field specimens can be made if serological tests are done before mice are moribund.
机译:按顺序滴定感染了以下病毒株-杜贝(一种新的虫媒病毒),刚果(与克里米亚出血热病毒有关),黄热病,登革热1和登革热2的乳鼠的脑和肝中感染性病毒和补体固定抗原的滴定感染后滴度逐渐升高。在小鼠表现出感染的临床迹象之前很久就证明了高滴度的感染性病毒和补体固定抗原。建议如果在小鼠垂死之前进行血清学检测,可以从临床和田间标本中早期分离和鉴定虫媒病毒。

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