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Evaluation of a Red Cell Agglutination Test for Detection of Australia Antigen (HB Ag)

机译:用于检测澳大利亚抗原(HB Ag)的红细胞凝集试验的评估

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An investigational red cell agglutination (RCA) test was evaluated for sensitivity in detecting and titering hepatitis B antigen (HB Ag) in comparison with two counterelectrophoresis (CEP) systems and a solid-phase radioimmunoassay (RIA). The RCA procedure was found to be significantly more sensitive than the CEP methods and compares favorably in sensitivity with the solid-phase RIA, detecting even lower concentrations of the HB Ag. Since the RCA test can be completed in 2 to 3 h and requires relatively inexpensive equipment, it offers a highly sensitive and rapid procedure suitable for use in blood banks to screen donors or detect low levels of antigen in serum of patients.
机译:与两个对电泳(CEP)系统和固相放射免疫分析(RIA)相比,评估了研究性红细胞凝集(RCA)测试在检测和滴定乙型肝炎抗原(HB Ag)方面的敏感性。发现RCA程序比CEP方法灵敏得多,并且在灵敏度上与固相RIA相当,可以检测到甚至更低浓度的HB Ag。由于RCA测试可以在2到3小时内完成,并且需要相对便宜的设备,因此它提供了一种高度灵敏,快速的程序,适合在血库中用于筛选供体或检测患者血清中的低水平抗原。

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