Production of Sterigmatocystin by Some Species of the Genus Aspergillus and Its Toxicity to Chicken Embryos

H. W. Schroeder; W. H. Kelton

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Production of Sterigmatocystin by Some Species of the Genus Aspergillus and Its Toxicity to Chicken Embryos

机译：几种曲霉属菌产生去角质毒素及其对鸡胚的毒性

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Sterigmatocystin was produced by 59% of Aspergillus flavus cultures and by 16% of A. parasiticus cultures. All sterigmatocystin-producing cultures of the A. flavus group also simultaneously produced aflatoxin or O-methylsterigmatocystin. Sterigmatocystin was produced by A. chevalieri, A. ruber, and A. amstelodami, species not previously reported to produce the compound. In 5-day-old chicken embryos, the no-effect level of toxicity of sterigmatocystin was between 1 and 2 μg/egg; the mean lethal dose was 5 to 7 μg; and 90 to 100% of the embryos were killed with 10 μg. Teratogenic effects and weight reduction were generally associated with nonlethal doses.

机译：黄曲霉培养物产生59％的黄曲霉菌和副寄生曲霉培养产生16％的曲霉毒素。黄曲霉组的所有产生葡萄球菌毒素的培养物也同时产生黄曲霉毒素或O-甲基葡萄球菌毒素。 Sterigmatocystin是由A.chevalieri，A.ruber和A.amstelodami产生的，以前没有报道可产生该化合物。在5天大的鸡胚胎中，司空菌毒素的毒性无效水平为1至2μg/鸡蛋。平均致死剂量为5至7微克; 10μg杀死90至100％的胚胎。致畸作用和体重减轻通常与非致死剂量有关。

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《Applied Microbiology》 |1975年第4期|共3页
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H. W. Schroeder; W. H. Kelton;
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6. Production of Sterigmatocystin by Some Species of the Genus Aspergillus and Its Toxicity to Chicken Embryos [O] . H. W. Schroeder, W. H. Kelton 1975

机译：几种曲霉属菌产生去角质毒素及其对鸡胚的毒性
7. Production of Sterigmatocystin by Some Species of the Genus Aspergillus and Its Toxicity to Chicken Embryos [O] . H. W. Schroeder, W. H. Kelton 1975

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Production of Sterigmatocystin by Some Species of the Genus Aspergillus and Its Toxicity to Chicken Embryos

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