• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Applied Microbiology >Circular Bacteriocins: Biosynthesis and Mode of Action
【24h】

Circular Bacteriocins: Biosynthesis and Mode of Action

机译：环状细菌素：生物合成和作用方式

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Circular bacteriocins are a group of N-to-C-terminally linked antimicrobial peptides, produced by Gram-positive bacteria of the phylum Firmicutes . Circular bacteriocins generally exhibit broad-spectrum antimicrobial activity, including against common food-borne pathogens, such as Clostridium and Listeria spp. These peptides are further known for their high pH and thermal stability, as well as for resistance to many proteolytic enzymes, properties which make this group of bacteriocins highly promising for potential industrial applications and their biosynthesis of particular interest as a possible model system for the synthesis of highly stable bioactive peptides. In this review, we summarize the current knowledge on this group of bacteriocins, with emphasis on the recent progress in understanding circular bacteriocin genetics, biosynthesis, and mode of action; in addition, we highlight the current challenges and future perspectives for the application of these peptides.
机译：环状细菌素是一组由N到C端连接的抗菌肽，由Firmir菌门的革兰氏阳性细菌产生。环状细菌素通常具有广谱抗菌活性，包括针对常见食源性病原体（如梭菌和李斯特菌）的抗菌活性。这些肽还因其高pH和热稳定性以及对许多蛋白水解酶的抗性而闻名，其特性使这组细菌素极有可能在潜在的工业应用中获得应用，并特别关注其生物合成作为合成的可能模型系统高度稳定的生物活性肽。在这篇综述中，我们总结了关于这组细菌素的当前知识，重点是在了解环状细菌素遗传学，生物合成和作用方式方面的最新进展。此外，我们重点介绍了这些肽的应用目前面临的挑战和未来前景。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号