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首页> 外文期刊>Applied Microbiology >Critical Knowledge Gaps in Our Understanding of Environmental Cycling and Transmission of Leptospira spp.
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Critical Knowledge Gaps in Our Understanding of Environmental Cycling and Transmission of Leptospira spp.

机译：我们对钩端螺旋体物种的环境循环和传播的理解中的关键知识缺口。

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摘要

Exposure to soil or water contaminated with the urine of Leptospira-infected animals is the most common way in which humans contract leptospirosis. Entire populations can be at high risk of leptospirosis while working in inundated fields, when engaging in aquatic sports, or after periods of heavy rainfall. The risk of infection after contact with these environmental sources depends on the ability of Leptospira bacteria to survive, persist, and infect new hosts. Multiple variables such as soil and water pH, temperature, and even environmental microbial communities are likely to shape the environmental conditions needed by the pathogen to persist. Here we review what is known about the environmental phase of the infectious Leptospira transmission cycle and identify knowledge gaps that will serve as a guide for future research.
机译：暴露于被钩端螺旋体感染的动物的尿液污染的土壤或水中是人类感染钩端螺旋体病的最常见方式。在淹没的田间工作，从事水上运动时或暴雨过后，整个人群都有钩端螺旋体病的高风险。与这些环境源接触后感染的风险取决于钩端螺旋体细菌存活，持久和感染新宿主的能力。诸如土壤和水的pH值，温度乃至环境微生物群落之类的多个变量可能会影响病原体持续生存所需的环境条件。在这里，我们回顾了有关传染性钩端螺旋体传播周期的环境阶段的已知知识，并确定了知识差距，这些知识差距将为将来的研究提供指导。

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