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Histopathological effect of Clostridium perfringens enterotoxin in the rabbit ileum.

机译:产气荚膜梭菌肠毒素在兔回肠中的组织病理学作用。

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Highly purified enterotoxin from Clostridium perfringens was found to have histopathological activity in the rabbit ileum. Unlike the action of cholera, Escherichia coli, and Shigella enterotoxins, epithelium was denuded from the tips of ileal villi at concentrations of the enterotoxin necessary to induce fluid accumulation in the rabbit. Whether or not this observed histopathology is essential for the diarrheal syndrome associated with Clostridium perfringens food poisoning remains unclear.
机译:发现来自产气荚膜梭菌的高度纯化的肠毒素在兔回肠中具有组织病理学活性。与霍乱,大肠埃希菌和志贺氏菌肠毒素的作用不同,回肠绒毛的顶端剥落的上皮在诱导兔体内积液所需的肠毒素浓度下脱落。尚不清楚这种观察到的组织病理学对于与产气荚膜梭状芽孢杆菌食物中毒有关的腹泻综合征是否必要。

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