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首页> 外文期刊>Infection and immunity >Analysis of unidirectional fluxes of sodium during diarrhea induced by Clostridium perfringens enterotoxin in the rat terminal ileum.
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Analysis of unidirectional fluxes of sodium during diarrhea induced by Clostridium perfringens enterotoxin in the rat terminal ileum.

机译：大鼠终末回肠产气荚膜梭菌肠毒素诱导的腹泻过程中钠的单向通量分析。

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摘要

Net intestinal transport of sodium in vivo, in control and enterotoxin (Clostridium perfringens)-treated rats, was resolved into two unidirectional fluxes, influx from and efflux into the lumen of the terminal ileum. In rats treated with the toxin, sodium influx remained similar to control values even during fluid and electrolyte loss to the lumen. Net loss of sodium was shown to be due to nearly a twofold increase in sodium efflux to the lumen in toxin-treated animals. There was only slight histopathological damage to the mucosa, especially noticeable at the tips of villi.
机译：在对照组和肠毒素（Clostridium perfringens）治疗的大鼠中，钠在体内的肠内净肠运输被分解为两个单向通量，即从回肠末端腔内流入和流出。在用毒素治疗的大鼠中，即使在管腔内液体和电解质流失期间，钠的流入仍保持与对照值相似。钠的净损失显​​示是由于毒素治疗动物的内腔钠流出增加了将近两倍。粘膜仅有轻微的组织病理学损害，在绒毛尖端尤为明显。

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