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首页> 外文期刊>Infection and immunity >Effect of systemic BCG infection in syrian golden hamsters.
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Effect of systemic BCG infection in syrian golden hamsters.

机译:全身性卡介苗感染对叙利亚黄金仓鼠的影响。

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The response of Syrian golden hamsters to systemic infection with several doses of Mycobacterium bovis (strain BCG) was assessed. Large numbers of organisms (10(7)), injected intravenously, were lethal for hamsters, whereas all animals survived infection with 10(4) colony-forming units of BCG. Animals responded immunologically to purified protein derivative as assessed by increased footpad swelling and splenic lymphocyte proliferation. The immediate cause of death was a diffuse granulomatous interstitial pneumonia.
机译:评估了叙利亚金仓鼠对几种剂量牛分枝杆菌(BCG株)的全身感染的反应。静脉内注射的大量生物体(10(7))对仓鼠具有致死性,而所有动物都被10(4)BCG菌落形成单位感染而幸免。通过足垫肿胀和脾淋巴细胞增生评估,动物对纯化的蛋白衍生物产生免疫反应。死亡的直接原因是弥漫性肉芽肿性间质性肺炎。

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