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首页> 外文期刊>Infection and immunity >Localization of Bacteria in the Gastrointestinal Tract: a Possible Explanation of Intestinal Spirochaetosis
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Localization of Bacteria in the Gastrointestinal Tract: a Possible Explanation of Intestinal Spirochaetosis

机译：细菌在胃肠道中的定位：肠道螺旋藻病的可能解释。

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The large intestine of rats and dogs was examined by light and electron microscopy. In both species localization of bacteria in specific areas of the tissue was observed. Fusiform bacteria mixed with spirochaetes were seen at the opening of the crypts into the large bowel. However, at the base of the crypts homogeneous populations of spiral organisms were found; some crypts contained Borrelia-type spirochaetes, whereas others contained spiral bacteria with other morphology. Very few spiral bacteria, including those of the spirillum type, were seen in the lumen of the large intestine. Experiments in rats showed that mucosa-associated spiral organisms appeared in large numbers in the stools when diarrhea was induced with magnesium sulfate. These observations were taken as a basis for explaining intestinal spirochaetosis of dogs and other animals, a syndrome which has been frequently described and which, until now, has been considered to reflect pathogenicity of these organisms.
机译：通过光镜和电子显微镜检查大鼠和狗的大肠。在两种物种中，均观察到细菌在组织的特定区域中的定位。在隐窝进入大肠的开口处看到梭形细菌与螺旋体混合。然而，在隐窝的底部发现了螺旋生物的同质种群。一些隐窝含有 Borrelia 型螺旋体，而其他隐窝则包含其他形态的螺旋细菌。在大肠腔中很少见到螺旋菌，包括螺旋菌。大鼠实验表明，当硫酸镁引起腹泻时，粪便中大量出现与粘膜相关的螺旋菌。这些观察结果被用作解释狗和其他动物的肠螺旋体病的基础，该综合征已被频繁描述，并且直到现在还被认为反映了这些生物的致病性。

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