Effects of Clostridium perfringens enterotoxin on metabolic indexes of everted rat ileal sacs.

J L McDonel; C L Duncan

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Effects of Clostridium perfringens enterotoxin on metabolic indexes of everted rat ileal sacs.

机译：产气荚膜梭菌肠毒素对外翻大鼠回肠囊代谢指标的影响。

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Everted sacs of rat ileum were incubated in Ringer phosphate solution while oxygen uptake, glucose uptake, and lactate production were determined. Sacs treated with Clostridium perfringens enterotoxin, in the form of crude cell-free extract and purified protein, consumed significantly less oxygen than untreated sacs. However, the toxin-treated sacs took up glucose and produced lactate at levels that were not significantly different than those observed in controls. We conclude that oxidative metabolism is inhibited by the action of the toxin, whereas conversion of glucose to lactate via glycolysis seems unaffected

机译：将大鼠回肠的外翻囊在林格磷酸盐溶液中温育，同时测定氧吸收，葡萄糖吸收和乳酸的产生。用产气荚膜梭状芽孢杆菌肠毒素处理过的囊袋（无细胞粗提物和纯化的蛋白质形式）比未处理的囊袋消耗的氧气少得多。然而，经毒素处理的囊吸收葡萄糖并产生的乳酸水平与对照中观察到的水平没有显着差异。我们得出结论，该毒素的作用抑制了氧化代谢，而通过糖酵解将葡萄糖转化为乳酸似乎没有受到影响。

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《Infection and immunity》 |1975年第2期|共7页
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J L McDonel; C L Duncan;
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6. Effects of Clostridium perfringens enterotoxin on metabolic indexes of everted rat ileal sacs. [O] . J L McDonel, C L Duncan 1975

机译：产气荚膜梭菌肠毒素对外翻大鼠回肠囊代谢指标的影响。
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Effects of Clostridium perfringens enterotoxin on metabolic indexes of everted rat ileal sacs.

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