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首页> 外文期刊>Infection and immunity >Virulence of Two Mastitis Strains of Staphylococcus aureus in Bovine Skin: Enhancement by Growth in High Carbohydrate-High Salt Medium or in Raw Milk
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Virulence of Two Mastitis Strains of Staphylococcus aureus in Bovine Skin: Enhancement by Growth in High Carbohydrate-High Salt Medium or in Raw Milk

机译：牛皮肤中两个金黄色葡萄球菌的乳腺炎毒株的毒力：高碳水化合物-高盐培养基或生乳中的生长增强

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Cows were inoculated intradermally with two strains of Staphylococcus aureus, and the severity of the resulting skin lesions was assessed on the basis of size, degree of necrosis, and in some cases by measuring the area of inflammation in histological preparations of excised skin. At least 106 colony forming units were required to produce a detectable skin lesion, indicating that the cow has a resistance to staphylococcal skin infection comparable to man and rabbit. The severity of the lesions produced by the two strains correlated with their known virulence in the bovine udder as mastitis pathogens. A comparison between lesions produced by cocci grown in a stock laboratory medium and those grown in the high carbohydrate-high salt modified 110 medium showed that the virulence of cocci grown in the latter medium was enhanced. The comparable effect of milk to the modified 110 medium is discussed.
机译：用两株金黄色葡萄球菌皮内接种牛，并根据大小，坏死程度以及在某些情况下通过测量组织学中的炎症区域来评估所产生的皮肤损伤的严重程度切除皮肤的制剂。至少需要10 6 个菌落形成单位才能产生可​​检测的皮肤病灶，这表明母牛对葡萄球菌的皮肤感染的抵抗力与人和兔子相当。这两种菌株产生的病变的严重程度与其在牛乳腺中作为乳腺炎病原体的已知毒力有关。将在普通实验室培养基中生长的球菌和在高碳水化合物-高盐修饰的110培养基中生长的球菌产生的损伤进行比较，结果表明，在后者的培养基中生长的球菌的毒性得到增强。讨论了牛奶与改性110培养基的可比效果。

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