Immunological Sequelae of Trichinella spiralis Infection in Mice II. Potentiation of Cell-Mediated Response to BCG After Infection with Trichinella spiralis

R. H. Cypess; J. A. Molinari; J. L. Ebersole; A. S. Lubiniecki

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Immunological Sequelae of Trichinella spiralis Infection in Mice II. Potentiation of Cell-Mediated Response to BCG After Infection with Trichinella spiralis

机译：旋毛虫感染小鼠的免疫后代II。旋毛虫感染后细胞介导的对卡介苗反应的增强作用

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Mice were infected with 200 Trichinella spiralis 14 days after intravenous administration of 4 × 106 viable BCG cells. Individual groups were tested for delayed hypersensitive footpad responses at 14, 20, 29, 57, or 85 days after T. spiralis infection. An initial suppression in the 14-day test group was observed; however, mice tested at later time intervals exhibited potentiation of the 24-h footpad reaction to old tuberculin over that elicited by appropriate controls. This suggested that T. spiralis induces a potentiation of the cellular immune response to BCG. Adoptive transfer studies support the cell-mediated nature of the observed footpad reaction and indicated that the initial suppression was not due to physiological factors preventing the expression of the footpad swelling reaction.

机译：静脉内施用4×10 6 活性BCG细胞后14天，小鼠被200只 Trichinella spiralis 感染。在 T后第14、20、29、57或85天测试各个组的迟发性超敏足垫反应。螺旋菌感染。在14天的测试组中观察到最初的抑制;但是，在较晚的时间间隔进行测试的小鼠，其24h足垫对老结核菌素的反应增强了，而适当的对照所引起的反应却没有。这表明 T。螺旋藻诱导了细胞对卡介苗的免疫应答增强。过继转移研究支持观察到的足垫反应的细胞介导性质，并表明最初的抑制作用不是由于生理因素阻止了足垫肿胀反应的表达。 展开▼

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《Infection and immunity》 |1974年第1期|共4页

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R. H. Cypess; J. A. Molinari; J. L. Ebersole; A. S. Lubiniecki;
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中图分类医学免疫学;

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1. Immunological sequelae of Trichinella spiralis infection in mice: effect of viability and route of BCG administration on nematode-induced immunopotentiation. [J] . J A Molinari, R H Cypess Infection and immunity . 1975,第5期

机译：小鼠Trichinella Spiralis感染的免疫学后：BCG施用活力与途径对线虫诱导的免疫抑制的影响。

2. Immunological sequelae of Trichinella spiralis infection in mice: effect of viability and route of BCG administration on nematode-induced immunopotentiation. [J] . J A Molinari, R H Cypess Infection and immunity . 1975,第5期

机译：小鼠Trichinella Spiralis感染的免疫学后：BCG施用活力与途径对线虫诱导的免疫抑制的影响。

3. Immunological sequelae of Trichinella spiralis infection in mice: effect of viability and route of BCG administration on nematode-induced immunopotentiation. [J] . J A Molinari, R H Cypess Infection and immunity . 1975,第5期

机译：小鼠Trichinella Spiralis感染的免疫学后：BCG施用活力与途径对线虫诱导的免疫抑制的影响。

4. Unusual Developmental Pattern of Expression of Enzymes Involved in DNA Biosynthesis in Trichinella spiralis and Trichinella pseudospiralis [C] . Magdalena Dqbrowska, Barbara Gotos, Elzbieta Walajtys-Rode, NATO advanced workshop on detection of bacteria, viruses, parasites and fungi . 2010

机译：在Trichinella螺螺生物合成中参与DNA生物合成的酶表达的不寻常发育模式，螺旋藻藻素和Trichinella pseudospiralis

5. Modulation of delayed-type hypersensitivity in mice during infection with Trichinella pseudospiralis or Trichinella spiralis. [D] . Kennedy, Rebecca Ruth. 1989

机译：小鼠旋毛虫或旋毛虫感染期间迟发型超敏反应的调节。

6. Immunological Sequelae of Trichinella spiralis Infection in Mice II. Potentiation of Cell-Mediated Response to BCG After Infection with Trichinella spiralis [O] . R. H. Cypess, J. A. Molinari, J. L. Ebersole, 1974

机译：旋毛虫感染小鼠的免疫后代II。旋毛虫感染后细胞介导的对卡介苗反应的增强作用

7. The Response of Mice to Infection by the Parasitic Nematode Trichinella: A Comparison of Trichinella Spiralis and Trichinella Pseudospiralis [O] . Anderson Barry Clayton 2002

机译：寄生线虫旋毛虫对小鼠的感染反应：旋毛虫和旋毛虫的比较

8. Assessment of Host Resistance to 'Trichinella spiralis' in Mice FollowingPreinfection Exposure to 2,3,7,8-TCDD [R] . Luebke, R. W., Copeland, C. B., Diliberto, J. J., 1994

机译：在感染2,3,7,8-TCDD后对小鼠'旋毛虫'寄主抗性的评估

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2. 旋毛虫诱导的非特异性免疫对伯氏疟原虫感染小鼠小肠组织免疫反应的调节 [J] . 梅旭 ,叶展鸿 ,吕芳丽 . 中华地方病学杂志 . 2020,第005期

3. 急性肠道旋毛虫感染后小鼠和大鼠内脏敏感性变化比较 [J] . 王文峰 ,汪欢 ,钱伟 . 首都医科大学学报 . 2010,第003期

4. 旋毛虫肠道急性感染后小鼠内脏敏感性的变化 [J] . 龙艳芹 ,童晶晶 ,侯晓华 . 胃肠病学和肝病学杂志 . 2009,第004期

5. CD4+/CD25+T细胞与旋毛虫急性感染后大鼠的肠道免疫活化 [J] . 蔺蓉 ,丁震 ,马欢 . 临床消化病杂志 . 2011,第006期

6. 旋毛虫感染小鼠肠道免疫应答研究 [C] . LI Jing ,李静 ,程相朝 . 中国畜牧兽医学会兽医病理学分会第二十次学术研讨会暨中国病理生理学会动物病理生理专业委员会第十九次学术研讨会 . 2014

7. 共感染旋毛虫对伯氏疟原虫感染小鼠肝脏和小肠免疫病理的调节机制研究 [A] . 梅旭 . 2020

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Immunological Sequelae of Trichinella spiralis Infection in Mice II. Potentiation of Cell-Mediated Response to BCG After Infection with Trichinella spiralis

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