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Lipid metabolism of Borrelia hermsi.

机译:伯氏疏螺旋体的脂质代谢。

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The synthesis of complex lipids by Borrelia hermsi while growing in Kelly medium was investigated by labeling cultures with D-[14C]glucose or [14C]palmitic acid. Labeled glucose was incorporated into phosphatidyl choline, phosphatidyl glycerol, monogalactosyl diglyceride, cholesterol glucoside, and acylated cholesteryl glucoside. The fatty acid composition reflected that of the medium suggesting that this spirochete directly incorporates acyl chains unaltered from its external milieu. Furthermore, the distribution of labeled carbon between acyl groups (lipid-soluble) and water-soluble moieties indicates that there is no metabolic exchange between these two pools. The relationship of B. hermsi to other spirochetes is discussed in terms of lipid metabolism as a generic characteristic.
机译:通过用D- [14C]葡萄糖或[14C]棕榈酸标记培养物,研究了伯氏疏螺旋体在凯利培养基中生长时合成脂质的合成。将标记的葡萄糖掺入磷脂酰胆碱,磷脂酰甘油,单半乳糖基甘油二酸酯,胆固醇葡糖苷和酰化胆固醇酯糖苷中。脂肪酸组成反映了培养基的组成,表明该螺旋体直接并入了其外部环境未改变的酰基链。此外,标记的碳在酰基基团(脂溶性)和水溶性基团之间的分布表明这两个库之间没有代谢交换。关于脂代谢作为一般特征,讨论了赫氏芽孢杆菌与其他螺旋体的关系。

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