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首页> 外文期刊>Infection and immunity >Transmissible Disease, Probably Viral in Origin, Affecting the Amebocytes of the European Shore Crab, Carcinus maenas
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Transmissible Disease, Probably Viral in Origin, Affecting the Amebocytes of the European Shore Crab, Carcinus maenas

机译：传播性疾病，可能是病毒性传播，影响欧洲岸蟹，美人蕉的变形细胞

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摘要

A transmissible infection of the shore crab (“crabe enragée”), Carcinus maenas, was discovered in one of about 700 of this species collected by the Station Biologique, Roscoff, France. The infection has been transferred by subinoculation through four serial passages in crabs collected at Roscoff and through six more passages in C. maenas collected at Woods Hole, Mass. The agent causes abnormal cellular clotting, a drop in the peripheral amebocyte count, clumping of amebocytes in the peripheral tissue and blood, and abnormal behavior of the amebocytes of the infected animal on glass. Mortality over a period of some weeks is negligible. Electron microscopy shows characteristic virus particles, about 55 to 125 nm in size, in the infected amebocytes. The agent is present in large amounts in the whole blood and serum, is filterable, heat labile, and has been preserved in the frozen state. Final identification will depend upon purification, growth in tissue culture, and further electron microscopy.
机译：在法国Roscoff的Station Biologique收集的大约700个物种中，发现了一种传染性的岸蟹（“ crabeenragée”）， Carenaus maenas 。通过在Roscoff收集的螃蟹中的四个连续传代和在 C中的另外六个传代，通过亚接种转移了感染。在马萨诸塞州伍兹霍尔（Woods Hole）收集到的maenas 。该病原会引起异常的细胞凝结，外周血白细胞数量下降，外周组织和血液中的血白细胞结块以及感染动物在玻璃杯上的血白细胞的异常行为。几周内的死亡率可以忽略不计。电子显微镜显示感染的变形细胞中特征性病毒颗粒，大小约为55至125 nm。该试剂大量存在于全血和血清中，是可过滤的，热不稳定的，并已以冷冻状态保存。最终鉴定将取决于纯化，组织培养中的生长以及进一步的电子显微镜检查。

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