首页> 外文期刊>Infection and immunity >Mycoplasma-Associated Induction of Interferon in Ovine Leukocytes
【24h】

Mycoplasma-Associated Induction of Interferon in Ovine Leukocytes

机译:支原体相关的羊白细胞干扰素诱导

获取原文
           

摘要

A mycoplasmal species, Acholeplasma laidlawii, isolated as a contaminant from a fetal lamb kidney cell line, was shown to be associated with the induction of interferon in cultures of ovine peripheral blood leukocytes. Broth cultures of the mycoplasma induced between 20 and 230 U of interferon per ml in leukocytes from two adult ewes. The amount of interferon produced correlated with the inoculum size of mycoplasma. Interferon production was associated with replication of the mycoplasma in the leukocyte cultures. Interferon was not induced by sterile mycoplasmal broth, a cell-free filtrate of the mycoplasmal cultures, or heat-inactivated mycoplasmas. The antiviral substance was characterized as interferon by the usual criteria.
机译:从胎羊肾细胞系中分离出的一种支原体种 Acholeplasma laidlawii 被作为一种污染物与绵羊外周血白细胞培养物中的干扰素诱导有关。支原体的肉汤培养物在来自两只成年母羊的白细胞中每毫升诱导20至230 U干扰素。产生的干扰素量与支原体的接种量有关。干扰素的产生与白细胞培养物中支原体的复制有关。无菌支原体肉汤,支原体培养物的无细胞滤液或热灭活的支原体不会诱导干扰素。通过常规标准将抗病毒物质表征为干扰素。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号