Plasmid-linked ampicillin resistance in haempohilus influenza type b.

L P Elwell; J De Graaff; D Seibert; S Falkow

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Plasmid-linked ampicillin resistance in haempohilus influenza type b.

机译：质粒连接的氨苄西林对b型流感嗜血杆菌的耐药性。

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Four ampicillin-resistant, beta-lactamase-producing strains of Haempohilus influenzae type b were examined for the presence of plasmid deoxyribonucleic acid (DNA). Three resistant strains contained a 30 x 10-6-dalton (30Mdal) plasmid and one resitant strain contained a 3-Mdal plasmid. The ampicillin-sensitive Haemophilus strains examined did not contain plasmid DNA. Transformation of a sensitive H. influenzae strain to ampicillin resistance with isolated plasmid DNA preparations revealed that the structural gene for beta-lactamase resided on both plasmid species. DNA-DNA hybridization studies showed that the 30-Mdal Haemophilus plasmid contained the ampicillin translocation DNA segment (TnA) found on some R-factors of enteric origin of the H. influenzae plasmids.

机译：检查了四个耐产氨苄青霉素，产生β-内酰胺酶的乙型流感嗜血杆菌，检测它们是否存在质粒脱氧核糖核酸（DNA）。 3株抗性菌株含有30×10-6道尔顿（30Mdal）质粒，而一种抗性菌株含有3-Mdal质粒。所检查的对氨苄青霉素敏感的嗜血杆菌菌株不含质粒DNA。用分离的质粒DNA制备物将敏感的流感嗜血杆菌菌株转化为氨苄青霉素抗性表明，β-内酰胺酶的结构基因存在于两种质粒中。 DNA-DNA杂交研究表明，30-Mdal嗜血杆菌质粒含有在流感嗜血杆菌质粒的一些肠源性R因子上发现的氨苄青霉素易位DNA片段（TnA）。

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《Infection and immunity》 |1975年第2期|共7页
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L P Elwell; J De Graaff; D Seibert; S Falkow;
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1. Plasmid-linked ampicillin resistance in haempohilus influenza type b. [J] . L P Elwell, J De Graaff, D Seibert, Infection and immunity . 1975,第2期

机译：质粒连接的氨苄西林对b型流感嗜血杆菌的耐药性。
2. Worldwide variation in the incidence of Haemophilus influenzae type b meningitis and its association with ampicillin resistance. [J] . Gessner BD European journal of clinical microbiology and infectious diseases: Official publication of the European Society of Clinical Microbiology . 2002,第2期

机译：全球范围内的b型流感嗜血杆菌脑膜炎发病率及其与氨苄西林耐药性有关。
3. Pandemic preparedness in Hawaii: a multicenter verification of real-time RT-PCR for the direct detection of influenza virus types A and B. [J] . Whelen AC, Bankowski MJ, Furuya G, Public health reports . 2010,第Suppla2期

机译：夏威夷的大流行防范：用于直接检测A型和B型流感病毒的实时RT-PCR的多中心验证。
4. Sources of resistance to Sclerotinia sclerotiorum in Brassica napus and B. juncea germplasm for China and Australia [C] . LI Caixia, LI Hua, Krishnapillai Sivasithamparam, Proceedings of the 12th International Rapeseed Congress: Sustainable Development in Cruciferous Oilseed Crops Production . 2007

机译：中国和澳大利亚的甘蓝型油菜和芥菜种质资源对核盘菌核盘菌的抗性来源
5. Effect of tetracycline resistance genes on transfer and stability of ampicillin resistance genes in Salmonella enteritidis. [D] . Fontana, John Leonard. 2000

机译：四环素抗性基因对肠炎沙门氏菌氨苄青霉素抗性基因转移和稳定性的影响。
6. Plasmid-linked ampicillin resistance in haempohilus influenza type b. [O] . L P Elwell, J De Graaff, D Seibert, 1975

机译：质粒连接的氨苄西林在b型流感嗜血杆菌中的耐药性。
7. Plasmid-linked ampicillin resistance in haempohilus influenza type b [O] . L P Elwell, J De Graaff, D Seibert, 1975

机译：血红蛋白流感型B型中的质粒连接的氨苄青霉素抗性

Plasmid-linked ampicillin resistance in haempohilus influenza type b.

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