Modified polyriboinosinic-polyribocytidylic acid, an immunological adjuvant.

W E Houston; C L Crabbs; E L Stephen; H B Levy

首页> 外文期刊>Infection and immunity >Modified polyriboinosinic-polyribocytidylic acid, an immunological adjuvant.

【24h】

Modified polyriboinosinic-polyribocytidylic acid, an immunological adjuvant.

机译：修饰的核糖肌苷-聚核糖酸，一种免疫佐剂。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Stabilization of polyriboinosinic-polyribocytidylic acid against enzymatic hydrolysis by addition of poly-1-lysine and carboxymethylcellulose (PICLC) resulted in a compound with marked adjuvanticity. The primary antibody response of rhesus monkeys to formalin-inactivated Venezuelan equine encephalomyelitis virus vaccine was significantly potentiated if the vaccine was combined with PICLC prior to vaccination. The antibody response was maintained at a significantly higher level than controls for 2.5 months postvaccination and paralleled immunological responses reported for live, attenuated (TC-83) vaccine.

机译：通过添加聚-1-赖氨酸和羧甲基纤维素（PICLC）来稳定多核糖苷酸-多核糖酸对酶水解的稳定性，从而得到具有明显佐剂性的化合物。如果在接种疫苗前将疫苗与PICLC组合，则恒河猴对福尔马林灭活的委内瑞拉马脑脊髓炎病毒疫苗的一抗反应显着增强。疫苗接种后2.5个月，抗体应答维持在显着高于对照组的水平，并且报道了减毒活疫苗（TC-83）的平行免疫应答。

著录项

来源
《Infection and immunity》 |1976年第1期|共2页
作者
W E Houston; C L Crabbs; E L Stephen; H B Levy;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类医学免疫学;
关键词

相似文献

外文文献
中文文献
专利

1. Modified polyriboinosinic-polyribocytidylic acid complex: sustained interferonemia and its physiological associates in humans. [J] . K J Champney, D P Levine, H B Levy, Infection and immunity . 1979,第3期

机译：修饰的聚核糖肌苷-聚核糖苷酸复合物：持续性干扰素血症及其在人体中的生理联系。
2. Modified polyriboinosinic-polyribocytidylic acid complex: sustained interferonemia and its physiological associates in humans. [J] . K J Champney, D P Levine, H B Levy, Infection and immunity . 1979,第3期

机译：修饰的聚核糖肌苷-聚核糖苷酸复合物：持续性干扰素血症及其在人体中的生理联系。
3. Not all polyriboinosinic-polyribocytidylic acids (Poly I:C) are equivalent for inducing maturation of dendritic cells: implication for alpha-type-1 polarized DCs. [J] . Avril T, de-Tayrac M, Leberre C, Journal of immunotherapy . 2009,第4期

机译：并非所有的聚核糖苷酸-多核糖酸（Poly I：C）都等同于诱导树突状细胞成熟：这意味着α-1型极化DC。
4. The Effects of Feeding Acidified Milk on Holstein Calves Growth Performance, Blood Immunologic Function, Fecal Microorganism Diversity [C] . YIN Shuxin, QU Yongli, YUAN Xue, The 6th International Symposium on Dairy Cow Nutrition and Milk Quality（第六届“奶牛营养与牛奶质量”国际研讨会）论文集 . -1

机译：喂养酸化牛奶对荷斯坦犊牛生长性能，血免疫功能，粪便微生物多样性的影响
5. In vitro reproductive-endocrine, and in vivo immunological responses to extracted oil sands-derived naphthenic acids. [D] . Leclair, Liane A. 2014

机译：对提取的油砂衍生的环烷酸的体外生殖内分泌和体内免疫学反应。
6. Modified polyriboinosinic-polyribocytidylic acid an immunological adjuvant. [O] . W E Houston, C L Crabbs, E L Stephen, 1976

机译：修饰的多核糖肌苷-多核糖酸一种免疫佐剂。
7. Modified polyriboinosinic-polyribocytidylic acid complex: induction of serum interferon, fever, and hypotension in rabbits. [O] . Gatmaitan, B G, Legaspi, R C, Levy, H B, 1980

机译：修饰的聚核糖肌苷-聚核糖苷酸复合物：在兔中诱导血清干扰素，发烧和低血压。
8. Modified Polyriboinosinic-Polyribocytidylic Acid, an Immunological Adjuvant. [R] . Houston, W. E., Crabbs, C. L., Stephen, E. L., 1976

机译：改良的聚核糖核苷 - 多聚胞苷酸，一种免疫佐剂。

Modified polyriboinosinic-polyribocytidylic acid, an immunological adjuvant.

摘要

著录项

相似文献

相关主题

期刊订阅