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Chronic Infections by Herpes Simplex Viruses and by the Horse and Cat Herpesviruses

机译:单纯疱疹病毒以及马和猫疱疹病毒的慢性感染

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Rabbit eyes experimentally infected with either type 1 or type 2 herpes simplex viruses occasionally released virus spontaneously. Injection of adrenalin was not highly effective for stimulating virus release but did seem to have a slight and erratic activating capacity. No spontaneous virus release were detected from the eyes of six cats infected with cat herpesvirus, but, when adrenalin was administered, an episode of virus release did ensue in one animal. Rabbit spinal cords could be chronically infected with either herpes simplex virus type 2 or equine herpesvirus type 2. The viruses could be reisolated over subsequent months from about half the animals without prior stimulation; the interval between inoculation of trypsinized spinal tissue into tissue cultures and the development of cytopathic effect was often long—more than 4 weeks in some cases.
机译:实验性感染1型或2型单纯疱疹病毒的兔眼偶尔会自发释放病毒。注射肾上腺素对刺激病毒释放不是很有效,但似乎具有轻微且不稳定的激活能力。从感染了猫疱疹病毒的六只猫的眼睛中未检测到自发病毒释放,但是,当施用肾上腺素时,在一只动物中确实发生了病毒释放。可以用2型单纯疱疹病毒或2型马疱疹病毒长期感染兔脊髓。在接下来的几个月中,可以从大约一半的动物中重新分离出这种病毒,而无需事先刺激。胰蛋白酶化的脊柱组织接种到组织培养物中与细胞病变作用的发展之间的间隔通常很长-在某些情况下超过4周。

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