Identification of a Canine Adenovirus (Infectious Canine Hepatitis Virus) Inhibitor in Dog Liver Extracts as Arginase

L. E. Carmichael

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Identification of a Canine Adenovirus (Infectious Canine Hepatitis Virus) Inhibitor in Dog Liver Extracts as Arginase

机译：在狗肝提取物中作为精氨酸酶的犬腺病毒（传染性犬肝炎病毒）抑制剂的鉴定

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Extracts of canine liver inhibited growth of infectious canine hepatitis (ICH) virus, a canine adenovirus. Purified extracts from mammalian, but not avian, liver tissue contained the inhibitor, and evidence is presented that the inhibitory factor is the enzyme arginase (arginine ureohydrolase). This study further emphasized the need for arginine in adenovirus growth and may explain some of the difficulties in isolating small amounts of ICH virus from suspensions of liver.

机译：犬肝提取物抑制犬腺病毒感染性犬肝炎（ICH）病毒的生长。来自哺乳动物而非禽类肝组织的纯化提取物含有抑制剂，并且有证据表明抑制因子是精氨酸酶（精氨酸脲水解酶）。这项研究进一步强调了在腺病毒生长中需要精氨酸，并且可以解释从肝脏悬液中分离少量ICH病毒的一些困难。

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《Infection and immunity》 |1972年第3期|共7页
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L. E. Carmichael;
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6. Identification of a Canine Adenovirus (Infectious Canine Hepatitis Virus) Inhibitor in Dog Liver Extracts as Arginase [O] . L. E. Carmichael 1972

机译：在狗肝提取物中作为精氨酸酶的犬腺病毒（传染性犬肝炎病毒）抑制剂的鉴定
7. Identification of a Canine Adenovirus (Infectious Canine Hepatitis Virus) Inhibitor in Dog Liver Extracts as Arginase [O] . L. E. Carmichael 1972

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Identification of a Canine Adenovirus (Infectious Canine Hepatitis Virus) Inhibitor in Dog Liver Extracts as Arginase

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