首页> 外文期刊>Infection and immunity >Immunodepression by Rowson-Parr virus in mice; lymphocyte markers and capping response of spleen and lymph node cells after infection.
【24h】

Immunodepression by Rowson-Parr virus in mice; lymphocyte markers and capping response of spleen and lymph node cells after infection.

机译:Rowson-Parr病毒对小鼠的免疫抑制作用;感染后淋巴细胞标志物和脾和淋巴结细胞的加帽反应。

获取原文
           

摘要

Infection with Rowson-Parr virus (RPV) induced a rapid reduction in the number of immunoglobulin-positive and theta antigen-positive cells detectable by immunofluorescence in the spleens of susceptible BALB/c mice. The changes produced by RPV infection in the lymph nodes were different, since the number of immunoglobulin-positive cells was increased and the proportion of theta-positive cells remained unchanged. However, the ability of immunoglobulin-bearing cells to redistribute their receptors into caps was reduced in both types of lymphoid tissue. A similar pattern of changes was produced by infection with Friend leukemia complex, from which RPV was originally obtained. These effects of RPV and Friend leukemia complex may contribute to the immunodepressed state of infected mice.
机译:在易感的BALB / c小鼠脾脏中,用Rowson-Parr病毒(RPV)感染导致免疫球蛋白可检测的免疫球蛋白阳性和theta抗原阳性细胞数量迅速减少。 RPV感染在淋巴结中产生的变化是不同的,因为免疫球蛋白阳性细胞的数量增加了,θ阳性细胞的比例保持不变。但是,在两种类型的淋巴组织中,带有免疫球蛋白的细胞将其受体重新分布到帽中的能力都降低了。 Friend白血病复合物的感染引起了类似的变化,最初是从RPV中获得的。 RPV和Friend白血病复合物的这些作用可能有助于感染小鼠的免疫抑制状态。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号