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首页> 外文期刊>Infection and immunity >Epidemiology of hepatitis B infection in Liberian infants.
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Epidemiology of hepatitis B infection in Liberian infants.

机译：利比里亚婴儿的乙型肝炎感染流行病学。

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To provide background for a hepatitis B vaccine efficacy trial, sera were collected from 0- to 4-year-old Liberian infants and their mothers, on two occasions an average of 14.75 months apart, and tested for serological markers of hepatitis B virus infection. The prevalence of the hepatitis B surface antigen (HBsAg) was 2.9% in the 0- to 6-month age group and 23% in infants 3 to 4 years of age. HBsAg persisted for the 14.75-month average follow-up period in 80.8% of the infants tested. The annual incidence of development of HBsAg was 18.9% for infants less than 1 year of age and 13.6% in infants 3 to 4 years of age. Infants born to HBsAg carrier mothers had significantly higher age-specific prevalence and incidence of hepatitis B virus infection. However, it was estimated that only a minor proportion of hepatitis B infections in Liberia are derived by vertical transmission from carrier mothers.
机译：为提供乙型肝炎疫苗功效试验的背景，平均两次间隔14.75个月的时间，从0至4岁的利比里亚婴儿及其母亲收集血清，并测试其乙型肝炎病毒感染的血清学指标。乙肝表面抗原（HBsAg）的患病率在0至6个月大的人群中为2.9％，在3至4岁的婴儿中为23％。在80.8％的接受测试的婴儿中，HBsAg持续了14.75个月的平均随访期。 1岁以下婴儿的HBsAg发生年发生率为18.9％，3至4岁婴儿的年发生率为13.6％。 HBsAg携带者母亲所生婴儿的年龄特定患病率和乙肝病毒感染发生率明显更高。但是，据估计，在利比里亚，只有很小一部分的乙型肝炎感染是由携带母体的垂直传播引起的。

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