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首页> 外文期刊>Infection and immunity >Experimental Rat model for Corynebacterium renale-induced pyelonephritis.
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Experimental Rat model for Corynebacterium renale-induced pyelonephritis.

机译:肾棒杆菌诱发的肾盂肾炎的实验大鼠模型。

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The laboratory rat was able to serve as a model for ascending pyelonephritis after implantation of a zinc disk coated with Corynebacterium renale into the urinary bladder because it satisfied three different criteria for infection. The production of an alkaline urine and the presence of significant numbers of C. renale in the kidneys, as well as distinct pyelonephritic lesions as revealed by histological examination, were observed in all rats infected with C. renale. Control rats that harbored sterile disks in their urinary bladders exhibited none of the above effects.
机译:该实验大鼠能够在肾脏中植入包被有棒状杆菌的锌盘后,成为上行肾盂肾炎的模型,因为它满足了三种不同的感染标准。在组织学检查中发现,在所有感染了肾小球藻的大鼠中观察到碱性尿的产生和肾脏中大量肾小球藻的存在,以及明显的肾盂肾小球病变。在膀胱中带有无菌盘的对照大鼠没有上述效果。

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