Affinity of Sendai virus for the inner ear of mice.

K Shimokata; Y NISHIYAMA; V Ito; Y Kimura; I Nagata

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Affinity of Sendai virus for the inner ear of mice.

机译：仙台病毒对小鼠内耳的亲和力。

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The direct immunofluorescent antibody method revealed that Sendai virus, which was thought to be most prevalent in respiratory diseases in mice, infected the inner ear of mice when the virus was injected intracerebrally. Specific immunofluorescence that indicated the presence of antigens of Sendai virus was observed in both perilymphatic and endolymphatic structures. The routes of virus spread are discussed. This experimental study, using newborn mice and Sendai virus, may be useful for the investigation of the pathogenesis of viral labyrinthitis not only because of the high frequency of inner ear infection, but also because of long-time survivors which facilitate prolonged observation.

机译：直接免疫荧光抗体法显示，仙台病毒被认为是在小鼠的呼吸系统疾病中最普遍的一种，当它被脑内注射时，它感染了小鼠的内耳。在淋巴和内淋巴结构中均观察到表明仙台病毒抗原存在的特异性免疫荧光。讨论了病毒传播的途径。这项利用新生小鼠和仙台病毒进行的实验研究，不仅因为内耳感染的频率高，而且由于长期存活的存活时间长，有利于长期观察，因此可用于研究病毒性迷路炎的发病机理。

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《Infection and immunity》 |1977年第2期|共3页
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K Shimokata; Y NISHIYAMA; V Ito; Y Kimura; I Nagata;
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中图分类医学免疫学;
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1. Paramyxovirus Sendai virus V protein counteracts innate virus clearance through IRF-3 activation, but not via interferon, in mice. [J] . Kiyotani K, Sakaguchi T, Kato A, Virology . 2007,第1期

机译：副粘病毒仙台病毒V蛋白通过IRF-3激活（而非通过干扰素）在小鼠中抵消先天病毒清除。
2. The properties of recombinant Sendai virus having the P gene of Sendai virus pi strain derived from BHK cells persistently infected with Sendai virus. [J] . Nishio M, Nagata A, Yamamoto A, Medical Microbiology and Immunology . 2006,第3期

机译：具有源于持续感染仙台病毒的BHK细胞的仙台病毒pi株的P基因的重组仙台病毒的特性。
3. Characterization of Sendai virus persistently infected L929 cells and Sendai virus pi strain: recombinant Sendai viruses having Mpi protein shows lower cytotoxicity and are incapable of establishing persistent infection [J] . Machiko Nishio, Masato Tsurudome, Morihiro Ito, Virology . 2003,第1期

机译：仙台病毒持续感染的L929细胞和仙台pi品系的表征：具有Mpi蛋白的重组仙台病毒显示出较低的细胞毒性，无法建立持续感染
4. Analysis of Innate Immune Responses in a Model of IgA Nephropathy Induced by Sendai Virus [C] . Michifumi Yamashita, Subba R. Chintalacharuvu, Noriyoshi Kobayash International Symposium on IgA Nephropathy . 2007

机译：仙台病毒诱导IgA肾病模型中的先天免疫应答分析
5. Innate immune responses to Sendai virus. [D] . Kim, Won-keun. 2013

机译：对仙台病毒的先天免疫反应。
6. Affinity of Sendai virus for the inner ear of mice. [O] . K Shimokata, Y NISHIYAMA, V Ito, 2018

机译：仙台病毒对小鼠内耳的亲和力。
7. Affinity of Sendai virus for the inner ear of mice [O] . K Shimokata, Y NISHIYAMA, V Ito, 1977

机译：仙台病毒对小鼠内耳的亲和力
8. Therapeutic Effects of Small-Particle Aerosols of Ribavirin on Parainfluenza (Sendai) Virus Infections of Mice. [R] . Larson, E. W., Stephen, E. L., Walker, J. S. 1976

机译：利巴韦林小颗粒气雾剂对小鼠副流感病毒（仙台）病毒感染的治疗作用。

Affinity of Sendai virus for the inner ear of mice.

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