Immunoglobulin A and secretory immunoglobulin A antibodies to purified type 1 Klebsiella pneumoniae pili in human colostrum.

C P Davis; C W Houston; R C Fader; R M Goldblum; E A Weaver; A S Goldman

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Immunoglobulin A and secretory immunoglobulin A antibodies to purified type 1 Klebsiella pneumoniae pili in human colostrum.

机译：人体初乳中纯化的1型肺炎克雷伯菌菌丝的免疫球蛋白A和分泌型免疫球蛋白A抗体。

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Immunoglobulin A antibodies with binding specificity for purified Klebsiella pneumoniae type 1 pili were detected by an enzyme-linked immunosorbent assay in 20 of 21 human samples (95%). The concentrations of secretory immunoglobulin A antibody in colostrum directed against the pili were calculated by comparison of experimental enzyme-linked immunosorbent assay values with values obtained from known secretory immunoglobulin A concentrations. The presence of antibodies to K. pneumoniae type 1 pili was confirmed by double diffusion-gel studies with selected specimens of colostrum. This study shows that in the majority of human colostral samples examined, secretory immunoglobulin A antibodies with specificity for K. pneumoniae type 1 pili can be commonly found in variable, but frequently high, concentrations.

机译：通过酶联免疫吸附法在21个人体样本中的20个（95％）中检测到了与纯化的1型肺炎克雷伯菌具有结合特异性的免疫球蛋白A抗体。通过将实验性酶联免疫吸附测定值与从已知的分泌型免疫球蛋白A浓度获得的值进行比较，计算出初乳中针对菌毛的分泌型免疫球蛋白A抗体的浓度。通过对初乳的选定标本进行双扩散凝胶研究，证实了1型肺炎克雷伯菌菌毛的抗体的存在。这项研究表明，在大多数接受检查的人类初乳样品中，通常可以以可变的但经常是高浓度的浓度发现对1型肺炎克雷伯菌具有特异性的分泌性免疫球蛋白A抗体。

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《Infection and immunity》 |1982年第2期|共6页
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C P Davis; C W Houston; R C Fader; R M Goldblum; E A Weaver; A S Goldman;
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中图分类医学免疫学;
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1. Inhibition of enteroaggregative Escherichia coli adhesion to HEp-2 cells by secretory immunoglobulin A from human colostrum. [J] . Fernandes RM, Carbonare SB, Carneiro-Sampaio MM, The Pediatric infectious disease journal . 2001,第7期

机译：人初乳分泌的免疫球蛋白A抑制肠聚合性大肠杆菌对HEp-2细胞的粘附。
2. Immunoglobulins in Nasal Secretions of Healthy Humans: Structural Integrity of Secretory Immunoglobulin A1 (IgA1) and Occurrence of Neutralizing Antibodies to IgA1 Proteases of Nasal Bacteria [J] . Line Kirkeby, Trine Tang Rasmussen, Jesper Reinholdt, Clinical and diagnostic laboratory immunology . 2000,第1期

机译：免疫球蛋白在健康人的鼻腔分泌物中：分泌性免疫球蛋白A1（IgA1）的结构完整性和针对鼻细菌IgA1蛋白酶的中和抗体的出现。
3. Somatic Hypermutation and Diverse Immunoglobulin Gene Usage in the Human Antibody Response to the Capsular Polysaccharide of Streptococcus pneumoniae Type 6B [J] . Jianhui Zhou, Kathleen R. Lottenbach, Stephen J. Barenkamp, Infection and immunity . 2004,第6期

机译：体细胞超突变和免疫球蛋白基因使用在人类对肺炎链球菌6B型荚膜多糖的抗体反应中。
4. Uncoiling Mechanism of Klebsiella pneumoniae Type 3 Pili Measured by using Optical Tweezers [C] . Feng-Jung Chen, Chia-Han Chan, Kuo-Liang Liu, Optical Trapping and Optical Micromanipulation IV; Proceedings of SPIE-The International Society for Optical Engineering; vol.6644 . 2007

机译：用光学镊子测量肺炎克雷伯菌3型菌毛的开卷机理
5. Purification of immunoglobulins, their bonding onto latex particles and the development of latex agglutination test for mouse immunoglobulin-G for monoclonal antibody assessment. [D] . Sompuram, Seshi Reddy. 1987

机译：免疫球蛋白的纯化，它们与乳胶颗粒的键合以及用于小鼠免疫球蛋白-G的乳胶凝集试验的发展，用于单克隆抗体评估。
6. Immunoglobulin A and secretory immunoglobulin A antibodies to purified type 1 Klebsiella pneumoniae pili in human colostrum. [O] . C P Davis, C W Houston, R C Fader, 1982

机译：人体初乳中纯化的1型肺炎克雷伯菌菌丝的免疫球蛋白A和分泌型免疫球蛋白A抗体。
7. Immunoglobulin A and secretory immunoglobulin A antibodies to purified type 1 Klebsiella pneumoniae pili in human colostrum [O] . C P Davis, C W Houston, R C Fader, 1982

机译：免疫球蛋白A和分泌物免疫球蛋白是人初乳中纯化1型克雷布氏菌肺炎的抗体
8. Influence of Secretory Immunoglobulin A and Purified Secretory Component of Dextran-Sucrase Activity of Streptococcus Mutans. [R] . Cole, J. S., Clark, G. E., Wistar, R. 1976

机译：分泌型免疫球蛋白a和变形链球菌葡聚糖 - 蔗糖酶活性的纯化分泌成分的影响。

Immunoglobulin A and secretory immunoglobulin A antibodies to purified type 1 Klebsiella pneumoniae pili in human colostrum.

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