Isolation and characterization of monoclonal antibodies to Shiga toxin.

D E Griffin; M K Gentry; J E Brown

首页> 外文期刊>Infection and immunity >Isolation and characterization of monoclonal antibodies to Shiga toxin.

【24h】

Isolation and characterization of monoclonal antibodies to Shiga toxin.

机译：志贺毒素单克隆抗体的分离和鉴定。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Hybridoma cell lines which produce monoclonal antibodies to Shiga toxin from Shigella dysenteriae 1 were prepared. The monoclonal antibodies were all of the immunoglobulin G1 isotype and differed in their ability to neutralize cytotoxicity and to bind to Shiga toxin in a solid-phase radioimmunoassay. When used for immunoblot analysis, these antibodies were able to identify specifically both nicked and unnicked Shiga toxin in crude lysates of S. dysenteriae.

机译：制备产生来自痢疾志贺氏菌1株的志贺氏菌毒素的单克隆抗体的杂交瘤细胞系。单克隆抗体均为免疫球蛋白G1同型，在固相放射免疫分析中，其中和细胞毒性和与志贺毒素结合的能力不同。当用于免疫印迹分析时，这些抗体能够特异性鉴定痢疾链球菌粗产物裂解液中有切口和无切口的志贺毒素。

著录项

来源
《Infection and immunity》 |1983年第1期|共4页
作者
D E Griffin; M K Gentry; J E Brown;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类医学免疫学;
关键词

相似文献

外文文献
中文文献
专利

1. Isolation and characterization of monoclonal antibodies to Shiga-like toxin II of enterohemorrhagic Escherichia coli and use of the monoclonal antibodies in a colony enzyme-linked immunosorbent assay. [J] . L P Perera, L R Marques, A D OBrien Journal of Clinical Microbiology . 1988,第10期

机译：肠出血性大肠杆菌的志贺氏样毒素II单克隆抗体的分离和鉴定，以及在菌落酶联免疫吸附测定中的应用。
2. Isolation and characterization of monoclonal antibodies directed against plant plasma membrane and cell wall epitopes: identification of a monoclonal antibody that recognizes extensin and analysis of the process of epitope biosynthesis in plant tissues and cell cultures. [J] . D J Meyer, C L Afonso, D W Galbraith Journal of cell biology . 1988,第1期

机译：针对植物质膜和细胞壁表位的单克隆抗体的分离和表征：识别可扩展蛋白的单克隆抗体的鉴定以及植物组织和细胞培养物中表位生物合成过程的分析。
3. Shiga toxin 2-specific but not shiga toxin 1-specific human monoclonal antibody protects piglets challenged with enterohemorrhagic Escherichia coli producing shiga toxin 1 and shiga toxin 2. [J] . Jeong KI, Tzipori S, Sheoran AS The Journal of Infectious Diseases . 2010,第7期

机译：志贺毒素2特异性而非志贺毒素1特异性人类单克隆抗体可保护经产肠出血性大肠杆菌攻击的仔猪，产生志贺毒素1和志贺毒素2。
4. Using Hydrophilic Interaction Chromatography - Mass Spectrometry for Heightened Product Characterization to Overcome Challenges with Hydrophobic Antibody Drug Conjugates and Monoclonal Antibodies [C] . Jacquelynn Smith, Matthew A. Lauber, Stephan M. Koza, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：使用亲水性相互作用色谱 - 质谱法加热的产品特征，以克服疏水性抗体药物缀合物和单克隆抗体的挑战
5. Isolation and characterization of peptides bearing the epitope for monoclonal antibody 1-C-6 from Swarm rat chondrosarcoma proteoglycan. [D] . Hejna, Michael John. 1988

机译：Swarm大鼠软骨肉瘤蛋白聚糖中带有单克隆抗体1-C-6抗原决定簇的肽的分离和鉴定。
6. Isolation and characterization of monoclonal antibodies to Shiga toxin. [O] . D E Griffin, M K Gentry, J E Brown 1983

机译：志贺毒素单克隆抗体的分离和鉴定。
7. Isolation and characterization of monoclonal antibodies to Shiga-like toxin II of enterohemorrhagic Escherichia coli and use of the monoclonal antibodies in a colony enzyme-linked immunosorbent assay [O] . L P Perera, L R Marques, A D OBrien 1988

机译：单克隆抗体对肠杆菌大肠杆菌的滋生毒素II的单克隆抗体的分离与表征及单克隆抗体在菌落酶联免疫吸附测定中的使用
8. Isolation and Characterization of Monoclonal Antibodies to Shiga Toxin. [R] . Griffin, D. E., Gentry, M. K., Brown, J. E. 1983

机译：志贺毒素单克隆抗体的分离与鉴定。

Isolation and characterization of monoclonal antibodies to Shiga toxin.

摘要

著录项

相似文献

相关主题

期刊订阅