Immunization against Porphyromonas gingivalis inhibits progression of experimental periodontitis in nonhuman primates.

G R Persson; D Engel; C Whitney; R Darveau; A Weinberg; M Brunsvold; R C Page

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Immunization against Porphyromonas gingivalis inhibits progression of experimental periodontitis in nonhuman primates.

机译：牙龈卟啉单胞菌的免疫作用可抑制非人类灵长类动物实验性牙周炎的进展。

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Periodontitis is a common infectious disease in which the attachment tissues of the teeth and their alveolar bone housing are destroyed, resulting in tooth loss. The gram-negative anaerobic microorganism Porphyromonas gingivalis has been closely linked to severe forms of the disease. We show for the first time that immunization of the primate Macaca fascicularis with killed P. gingivalis in Syntex Adjuvant Formulation-M inhibits progression of periodontal tissue destruction.

机译：牙周炎是一种常见的传染病，其中牙齿的附着组织及其牙槽骨腔被破坏，导致牙齿脱落。革兰氏阴性厌氧微生物牙龈卟啉单胞菌与该疾病的严重形式密切相关。我们首次表明，在Syntex佐剂配方-M中用杀死的牙龈卟啉单胞菌进行的灵长类猕猴的免疫接种抑制了牙周组织破坏的进展。

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《Infection and immunity》 |1994年第3期|共6页
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G R Persson; D Engel; C Whitney; R Darveau; A Weinberg; M Brunsvold; R C Page;
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中图分类医学免疫学;
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1. Effects of immunization with Porphyromonas gingivalis and Prevotella intermedia on progression of ligature-induced periodontitis in the nonhuman primate Macaca fascicularis. [J] . J L Ebersole, M Brunsvold, B Steffensen, Infection and immunity . 1991,第10期

机译：牙龈卟啉单胞菌和中间小球藻免疫接种对非人灵长类猕猴猕猴的结扎诱导的牙周炎进展的影响。
2. 1-Tetradecanol complex reduces progression of Porphyromonas gingivalis-induced experimental periodontitis in rabbits. [J] . Hasturk H, Jones VL, Andry C, Journal of Periodontology . 2007,第5期

机译：1-十四碳醇复合物可降低家兔牙龈卟啉单胞菌诱发的实验性牙周炎的进展。
3. Inhibitory effects of incadronate on the progression of rat experimental periodontitis by porphyromonas gingivalis infection. [J] . Tani Ishii N, Minamida G, Saitoh D, Journal of Periodontology . 2003,第5期

机译：萘甲酸钙对牙龈卟啉单胞菌感染大鼠实验性牙周炎进展的抑制作用。
4. Nuclear factor-KB p50 subunits in chronic periodontitis and Porphyromonas gingivalis lipopolysaccharide-pulsed dendritic cells [C] . Ravi Jotwani, Baljit S. Moonga, Siddharth Gupta, Conference on Skeletal Biology and Medicine . 2010

机译：核因子-KB P50慢性牙周炎和卟啉核苷酸的亚基血管脂多糖 - 脉冲树突细胞
5. Blockade of CXCR4 inhibits Porphyromonas gingivalis colonization in vivo and subsequent periodontal bone loss. [D] . Mc Intosh, Megan L. 2012

机译：CXCR4的阻断作用可在体内抑制牙龈卟啉单胞菌的定居，以及随后的牙周骨丢失。
6. Immunization against Porphyromonas gingivalis inhibits progression of experimental periodontitis in nonhuman primates. [O] . G R Persson, D Engel, C Whitney, 1994

机译：牙龈卟啉单胞菌的免疫作用可抑制非人类灵长类动物实验性牙周炎的进展。
7. Immunization against Porphyromonas gingivalis inhibits progression of experimental periodontitis in nonhuman primates [O] . G R Persson, D Engel, C Whitney, 1994

机译：对卟啉核糖菌的免疫抑制非人的灵长类动物实验期牙周炎的进展
8. Immunization with Porphyromonas Gingivalis Cysteine Protease: Effects onExperimental Gingivitis and Ligature-Induced Periodontitis in Macaca Fascicularis [R] . Moritz, A. J. 1997

机译：牙龈卟啉单胞菌半胱氨酸蛋白酶免疫对猕猴实验性牙龈炎和结扎诱导的牙周炎的影响

Immunization against Porphyromonas gingivalis inhibits progression of experimental periodontitis in nonhuman primates.

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