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Antimicrobial activity of two bactenecins against spirochetes.

机译:两种细菌素对螺旋体的抗菌活性。

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摘要

Bac5 and Bac7 are antimicrobial peptides of bovine neutrophils that act on enteric gram-negative bacteria. We report here that these two peptides immobilize and kill Leptospira interrogans and Leptospira biflexa with MBCs of 6 to 25 micrograms/ml. Conversely, although both peptides bind to Borrelia burgdorferi, the organism is resistant to their action.
机译:Bac5和Bac7是牛中性粒细胞的抗菌肽,可作用于肠革兰氏阴性细菌。我们在这里报告,这两个肽固定并杀死6至25微克/毫升的MBC的问号钩端螺旋体和钩端螺旋体。相反,尽管两种肽都结合伯氏疏螺旋体,但是该生物体对其作用有抗性。

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