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Combined inheritance of epithelial and erythrocyte receptors for Haemophilus influenzae.

机译:流感嗜血杆菌的上皮和红细胞受体结合遗传。

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Haemophilus influenzae type b expressing fimbriae showed no adherence to buccal epithelial cells and no agglutination of erythrocytes from three AnWj-negative siblings in one family. Hemagglutination of erythrocytes from 13 AnWj-positive members of the same family and from 24 controls was normal, and H. influenzae adhered well to buccal epithelial cells from them. These data indicate that the expression of epithelial and erythrocyte receptors for H. influenzae is inherited concomitantly. Combined with previous data (L. van Alphen, J. Poole, L. Geelen, and H. Zanen, Infect. Immun. 55:2355-2358, 1987), the results show that the receptor molecules on the surfaces of the epithelial cell and the erythrocyte are different but that the binding sites for the fimbriae of H. influenzae are similar.
机译:表达一个菌毛的b型流感嗜血杆菌显示对颊上皮细胞没有粘附,并且一个家庭中三个AnWj阴性兄弟姐妹的红细胞也没有凝集。来自同一家族的13个AnWj阳性成员和24个对照的红细胞的血细胞凝集是正常的,流感嗜血杆菌对它们的颊上皮细胞粘附良好。这些数据表明,流感嗜血杆菌的上皮和红细胞受体的表达是同时遗传的。结合先前的数据(L. van Alphen,J。Poole,L。Geelen和H.Zanen,Infect。Immun。55:2355-2358,1987),结果显示上皮细胞表面的受体分子流感嗜血杆菌的菌毛结合位点相似。

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