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首页> 外文期刊>Infection and immunity >Crossed immunoelectrophoretic analysis of Legionella pneumophila serogroup 1 antigens.
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Crossed immunoelectrophoretic analysis of Legionella pneumophila serogroup 1 antigens.

机译：嗜肺军团菌血清群1抗原的交叉免疫电泳分析。

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摘要

By crossed immunoelectrophoresis, 85 different antigens were demonstrated in sonicated preparations of Legionella pneumophila serogroup 1 (Lp1). The precipitin patterns of 82 anodic-migrating antigens were numbered and were designated the Lp1 reference system. Eleven antigens were stable to boiling, and seven of these were shown to be surface antigens. One heat-stable surface antigen (antigen no. 61) was highly reactive with limulus amoebocyte lysates and formed a precipitin resembling lipopolysaccharide. Serum from an isolation confirmed case of Lp1 infection and serogroup-specific rabbit antiserum reacted specifically with antigen no. 61, which was designated the serogroup-specific antigen. Normal human and rabbit sera commonly had antibodies to antigen no. 66 of the Lp1 reference system. This antigen is antigenically related to the "common antigen" of Pseudomonas aeruginosa.
机译：通过交叉免疫电泳，在肺炎军团菌血清群1（Lp1）的超声处理制剂中证实了85种不同的抗原。对82种阳极迁移抗原的沉淀模式进行了编号，并将其命名为Lp1参考系统。 11种抗原对煮沸稳定，其中7种是表面抗原。一种热稳定的表面抗原（抗原编号61）与变形细胞溶解物高度反应，并形成类似于脂多糖的沉淀素。分离出的血清证实了Lp1感染的情况，血清群特异性兔抗血清与抗原No.10特异性反应。 61，被指定为血清群特异性抗原。正常人和兔血清通常都具有针对抗原的抗体。 Lp1参考系统的66。该抗原与铜绿假单胞菌的“共同抗原”在抗原上相关。

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