Alteration of the immunoglobulin G subclass responses in mice to lipopolysaccharide: effects of nonbacterial proteins and bacterial membrane phospholipids or outer membrane proteins of Proteus mirabilis.

H Karch; J Gmeiner; K Nixdorff

首页> 外文期刊>Infection and immunity >Alteration of the immunoglobulin G subclass responses in mice to lipopolysaccharide: effects of nonbacterial proteins and bacterial membrane phospholipids or outer membrane proteins of Proteus mirabilis.

【24h】

Alteration of the immunoglobulin G subclass responses in mice to lipopolysaccharide: effects of nonbacterial proteins and bacterial membrane phospholipids or outer membrane proteins of Proteus mirabilis.

机译：小鼠对脂多糖的免疫球蛋白G亚类反应的改变：奇异变形杆菌的非细菌蛋白和细菌膜磷脂或外膜蛋白的影响。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The immunoglobulin M (IgM) and the IgG1, IgG2ab, and IgG3 subclasses of plaque-forming cells (PFC) specific for lipopolysaccharide (LPS) were measured after immunization of mice with LPS alone and compared with the responses to LPS in combination with nonbacterial proteins and with bacterial membrane phospholipid vesicles or two major outer membrane proteins from Proteus mirabilis. The relative numbers of IgG PFC belonging to the IgG1, IgG2, or IgG3 subclasses induced by immunization with LPS alone depended upon the type of LPS administered. Phospholipids and the proteins effected characteristic alterations in not only the strength but also the subclass of the IgG responses to LPS. The results suggest that the hydrophobic-hydrophilic nature or state of aggregation of the preparations plays a role in the induction of IgG1 and IgG2 subclasses of PFC specific for LPS. Complex formation with LPS and adjuvant was apparently necessary to obtain these effects.

机译：在单独用LPS免疫小鼠后，测量了免疫球蛋白M（IgM）和脂多糖（LPS）特异的噬菌斑形成细胞（PFC）的IgG1，IgG2ab和IgG3亚类，并将其与非细菌蛋白联合对LPS的反应进行比较以及细菌膜磷脂囊泡或两种来自变形杆菌的主要外膜蛋白。通过单独用LPS免疫诱导的属于IgG1，IgG2或IgG3亚类的IgG PFC的相对数量取决于所施用LPS的类型。磷脂和蛋白质不仅在强度上而且在对LPS的IgG响应的亚类方面都产生了特征性变化。结果表明，制剂的疏水亲水性质或聚集状态在对LPS特异的PFC的IgG1和IgG2亚类的诱导中起作用。与LPS和佐剂形成复合物显然是获得这些作用所必需的。

著录项

来源
《Infection and immunity》 |1983年第1期|共9页
作者
H Karch; J Gmeiner; K Nixdorff;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类医学免疫学;
关键词

相似文献

外文文献
中文文献
专利

1. Alteration of the immunoglobulin G subclass responses in mice to lipopolysaccharide: effects of nonbacterial proteins and bacterial membrane phospholipids or outer membrane proteins of Proteus mirabilis. [J] . H Karch, J Gmeiner, K Nixdorff Infection and immunity . 1983,第1期

机译：小鼠对脂多糖的免疫球蛋白G亚类反应的改变：奇异变形杆菌的非细菌蛋白和细菌膜磷脂或外膜蛋白的影响。
2. Antibody-producing cell responses to an isolated outer membrane protein and to complexes of this antigen with lipopolysaccharide or with vesicles of phospholipids from Proteus mirabilis. [J] . H Karch, K Nixdorff Infection and immunity . 1981,第3期

机译：产生抗体的细胞对分离的外膜蛋白以及该抗原与脂多糖或奇异变形杆菌磷脂囊泡的复合物的反应。
3. Immunoglobulin G subclass response of juvenile periodontitis subjects to principal outer membrane proteins of Actinobacillus actinomycetemcomitans. [J] . M E Wilson, R G Hamilton Infection and immunity . 1995,第3期

机译：少年牙周炎患者免疫球蛋白G亚类对放线放线杆菌的主要外膜蛋白的反应。
4. Towards Simulations of Outer Membrane Proteins in Lipopolysaccharide Membranes [C] . T. A. Soares, T. P. Straatsma International Conference of Computational Methods in Sciences and Engineering 2007(ICCMSE 2007); 20070925-30; Corfu(GR) . 2007

机译：模拟脂多糖膜中的外膜蛋白
5. Lipopolysaccharide assembly in Escherichia coli. Part A: Characterization of the function and biogenesis of the two-protein complex involved in LPS assembly at the outer membrane. Part B: Reconstitution of LPS transport across the periplasm via a trans-envelope protein complex [D] . Chng, Shu Sin 2010

机译：大肠杆菌中的脂多糖组装体。 A部分：表征LPS组装在外膜上的两种蛋白质复合物的功能和生物发生。 B部分：通过跨包膜蛋白复合物重建脂多糖跨周质的运输
6. Alteration of the immunoglobulin G subclass responses in mice to lipopolysaccharide: effects of nonbacterial proteins and bacterial membrane phospholipids or outer membrane proteins of Proteus mirabilis. [O] . H Karch, J Gmeiner, K Nixdorff 1983

机译：小鼠对脂多糖的免疫球蛋白G亚类应答的改变：奇异变形杆菌的非细菌蛋白和细菌膜磷脂或外膜蛋白的作用。
7. Immunoglobulin G subclass response of juvenile periodontitis subjects to principal outer membrane proteins of Actinobacillus actinomycetemcomitans [O] . M E Wilson, R G Hamilton 1995

机译：少年牙周炎对actinobacillus actinomyceteMco1的主要外膜蛋白质的免疫球蛋白G亚类响应
8. Antibody Response of Infected Mice to Outer Membrane Proteins of Pseudomonas aeruginosa [R] . Hedstrom, R. C., Pavlovskis, O. R., Galloway, D. R. 1984

机译：感染小鼠对铜绿假单胞菌外膜蛋白的抗体反应

Alteration of the immunoglobulin G subclass responses in mice to lipopolysaccharide: effects of nonbacterial proteins and bacterial membrane phospholipids or outer membrane proteins of Proteus mirabilis.

摘要

著录项

相似文献

相关主题

期刊订阅