Antigen-reactivity pattern of T-cell hybridomas from Mycobacterium bovis BCG-infected mice.

I Müller; S H Kaufmann

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Antigen-reactivity pattern of T-cell hybridomas from Mycobacterium bovis BCG-infected mice.

机译：来自牛分枝杆菌BCG感染小鼠的T细胞杂交瘤的抗原反应性模式。

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Lymph node cells from mice infected with live Mycobacterium bovis BCG were fused with BW5147 cells after short-term culturing in vitro. Both mycobacterium- and self-reactive T-cell hybridomas were identified. Some T-cell hybridoma clones displayed dual reactivity to self and to self plus mycobacterial antigen but did so to a different degree, indicating that infection with mycobacteria stimulates autoreactive immune responses.

机译：在体外短期培养后，将来自活牛分枝杆菌BCG感染小鼠的淋巴结细胞与BW5147细胞融合。鉴定了分枝杆菌和自反应性T细胞杂交瘤。一些T细胞杂交瘤克隆对自身以及对自身和分枝杆菌抗原均表现出双重反应，但程度不同，表明分枝杆菌感染会刺激自身反应性免疫反应。

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《Infection and immunity》 |1985年第3期|共3页
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I Müller; S H Kaufmann;
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中图分类医学免疫学;
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1. In vivo and in vitro administration of interleukin 2-containing preparation reverses T-cell unresponsiveness in Mycobacterium bovis BCG-infected mice. [J] . V Colizzi Infection and immunity . 1984,第1期

机译：体内和体外施用含白介素2的制剂可逆转牛分枝杆菌BCG感染小鼠的T细胞无反应性。
2. Spleen cell cytokine secretion in Mycobacterium bovis BCG-infected mice. [J] . K Huygen, D Abramowicz, P Vandenbussche, Infection and immunity . 1992,第7期

机译：牛分枝杆菌BCG感染小鼠的脾细胞细胞因子分泌。
3. Enhancement of resistance to infections by endotoxin-induced serum factor from Mycobacterium bovis BCG-infected mice. [J] . M A Parant, F J Parant, L A Chedid Infection and immunity . 1980,第3期

机译：内毒素诱导牛分枝杆菌BCG感染小鼠的血清因子对感染的抵抗力增强。
4. Isolated Strains of Nontuberculous Mycobacterium Interfere with Immune Responses Associated with Mycobacterium bovis BCG Vaccination [C] . Chunfang Wang, Huarui Qi, Xiuyun Jiang International Conference on Biotechnology, Chemical and Materials Engineering . 2014

机译：孤立的非萎缩分枝杆菌的菌株干扰与肉杆菌BCG疫苗接种的免疫应答
5. Patterns of Mycobacterium bovis infection and associated risk factors in Michigan white-tailed deer. [D] . Miller, RoseAnn. 2004

机译：密歇根州白尾鹿的牛分枝杆菌感染模式及相关危险因素。
6. Antigen-reactivity pattern of T-cell hybridomas from Mycobacterium bovis BCG-infected mice. [O] . I Müller, S H Kaufmann 1985

机译：来自牛分枝杆菌BCG感染小鼠的T细胞杂交瘤的抗原反应性模式。
7. Ineffective Cellular Immune Response Associated with T-Cell Apoptosis in Susceptible Mycobacterium bovis BCG-Infected Mice [O] . Kremer, Laurent, Estaquier, Jérôme, Wolowczuk, Isabelle, 2000

机译：与易感牛分枝杆菌BCG感染的小鼠中T细胞凋亡相关的无效的细胞免疫反应。

Antigen-reactivity pattern of T-cell hybridomas from Mycobacterium bovis BCG-infected mice.

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