Immunization with live recombinant Salmonella typhimurium aroA producing F1 antigen protects against plague.

P C Oyston; E D Williamson; S E Leary; S M Eley; K F Griffin; R W Titball

首页> 外文期刊>Infection and immunity >Immunization with live recombinant Salmonella typhimurium aroA producing F1 antigen protects against plague.

【24h】

Immunization with live recombinant Salmonella typhimurium aroA producing F1 antigen protects against plague.

机译：产活重组鼠伤寒沙门氏菌aroA产生F1抗原的免疫可预防鼠疫。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

An attenuated Salmonella typhimurium strain which expressed the F1 capsular antigen of Yersinia pestis was constructed by transformation of S. typhimurium SL3261 with plasmid pFGAL2a, a derivative of pUC18 which contained the caf1 gene without the leader sequence. The recombinant was used to vaccinate mice intragastrically and intravenously. The immunity induced was able to protect mice against challenge with a virulent strain of plague. Protection correlated with the induction of high titers of immunoglobulin G in serum samples and a specific T-cell response.

机译：表达鼠疫耶尔森氏菌F1荚膜抗原的减毒鼠伤寒沙门氏菌菌株是通过用质粒pFGAL2a转化鼠伤寒沙门氏菌SL3261构建的，该质粒是pUC18的衍生物，其中含有没有前导序列的caf1基因。该重组体用于在胃内和静脉内给小鼠接种疫苗。诱导的免疫力能够保护小鼠免受鼠疫的毒力攻击。保护与血清样品中高滴度免疫球蛋白G的诱导和特异性T细胞反应有关。

著录项

来源
《Infection and immunity》 |1995年第2期|共6页
作者
P C Oyston; E D Williamson; S E Leary; S M Eley; K F Griffin; R W Titball;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类医学免疫学;
关键词

相似文献

外文文献
中文文献
专利

1. Immunization with live recombinant Salmonella typhimurium aroA producing F1 antigen protects against plague. [J] . P C Oyston, E D Williamson, S E Leary, Infection and immunity . 1995,第2期

机译：产活重组鼠伤寒沙门氏菌aroA产生F1抗原的免疫可预防鼠疫。
2. Expression of the Yersinia pestis capsular antigen (F1 antigen) on the surface of an aroA mutant of Salmonella typhimurium induces high levels of protection against plague. [J] . R W Titball, A M Howells, P C Oyston, Infection and immunity . 1997,第5期

机译：鼠伤寒沙门氏菌aroA突变体表面上的鼠疫耶尔森氏菌荚膜抗原（F1抗原）的表达诱导了对鼠疫的高水平保护。
3. Immunization with live aroA recombinant Salmonella typhimurium producing invasin inhibits intestinal translocation of Yersinia pseudotuberculosis. [J] . M Simonet, N Fortineau, J L Beretti, Infection and immunity . 1994,第3期

机译：产生活菌素的aroA重组鼠伤寒沙门氏菌活疫苗的免疫作用可抑制假结核耶尔森氏菌的肠道移位。
4. Novel Bacterial Delivery System with Attenuated Salmonella typhimurium Carrying Plasmid Encoding Mtb Antigen 85A for Mucosal Immunization Establishment of Proof of Principle in TB Mouse Model [C] . SHREEMANTA K. PARIDA, KRIS HUYGEN, BERNHARD RYFFEL, International Conference on Natural Products and Molecular Medicine . 2005

机译：新型细菌输送系统，具有减毒沙门氏菌培养质粒编码MTB抗原85A，用于粘膜免疫，在TB小鼠模型中的原理证明
5. Salmonella Typhimurium Internalization in Fresh Produce under Plant Stress, and Inactivation of Internalized Salmonella Using Ultraviolet-C Irradiation and Chemical Disinfectants. [D] . Ge, Chongtao. 2012

机译：植物压力下新鲜农产品中的鼠伤寒沙门氏菌内在化，以及使用紫外线-C辐射和化学消毒剂灭活内在化的沙门氏菌。
6. Immunization with live recombinant Salmonella typhimurium aroA producing F1 antigen protects against plague. [O] . P C Oyston, E D Williamson, S E Leary, 1995

机译：产活重组鼠伤寒沙门氏菌aroA产生F1抗原的免疫可预防鼠疫。
7. Oral immunization of mice with attenuated Salmonella typhimurium aroA expressing a recombinant Mycoplasma hyopneumoniae antigen (NrdF) [O] . Fagan Peter K., Djordjevic Steve P., Chin James, 1997

机译：减毒鼠伤寒沙门氏菌aroA表达重组猪肺炎支原体抗原（NrdF）的小鼠口服免疫

Immunization with live recombinant Salmonella typhimurium aroA producing F1 antigen protects against plague.

摘要

著录项

相似文献

相关主题

期刊订阅