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首页> 外文期刊>Infection and immunity >Effect of pyocyanine, a pigment of Pseudomonas aeruginosa, on production of reactive nitrogen intermediates by murine alveolar macrophages.
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Effect of pyocyanine, a pigment of Pseudomonas aeruginosa, on production of reactive nitrogen intermediates by murine alveolar macrophages.

机译:铜绿假单胞菌的色素-花青素对鼠肺泡巨噬细胞产生活性氮中间体的影响。

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In this study we investigated the effect of pyocyanine, a pigment produced by Pseudomonas aeruginosa, on production of reactive nitrogen intermediates by macrophages. We found that addition of pyocyanine to cultures of murine alveolar macrophages inhibited the capacity of these cells to produce reactive nitrogen intermediates (measured as nitrite) in a dose-dependent manner without altering cell viability, cytokine-induced Ia expression, or production of tumor necrosis factor.
机译:在这项研究中,我们研究了由铜绿假单胞菌(Pseudomonas aeruginosa)产生的色素-花青素对巨噬细胞产生活性氮中间体的影响。我们发现,向鼠肺泡巨噬细胞培养物中添加花青素可抑制这些细胞以剂量依赖性方式产生反应性氮中间体(以亚硝酸盐计)的能力,而不会改变细胞活力,细胞因子诱导的Ia表达或肿瘤坏死的产生。因子。

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