Association of hydroxamate siderophore (aerobactin) with Escherichia coli isolated from patients with bacteremia.

J Z Montgomerie; A Bindereif; J B Neilands; G M Kalmanson; L B Guze

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Association of hydroxamate siderophore (aerobactin) with Escherichia coli isolated from patients with bacteremia.

机译：异羟肟酸铁载体（气杆菌素）与从菌血症患者分离的大肠杆菌的关联。

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Clinical isolates of Escherichia coli were examined for the presence of hydroxamate siderophore (aerobactin). The incidence of aerobactin-positive strains of E. coli from the blood was greater than the incidence of these strains isolated from other sites. The presence of aerobactin and the virulence of strains of E. coli in urinary tract infection were also examined in mice. The presence of aerobactin in the strains of E. coli correlated with virulence as measured by proportion of deaths but not with renal infection. These results suggest that the presence of aerobactin may be a significant factor in the invasion of the blood stream.

机译：检查了大肠杆菌的临床分离株是否存在异羟肟酸酯铁载体（航空细菌素）。血液中大肠杆菌的气杆菌素阳性菌株的发生率高于从其他部位分离出的这些菌株的发生率。还检查了小鼠中尿杆菌素的存在和大肠杆菌菌株在尿路感染中的毒力。大肠杆菌菌株中嗜气菌素的存在与致病力相关，而致病力是通过死亡比例来衡量的，但与肾脏感染无关。这些结果表明，航空细菌素的存在可能是血流入侵的重要因素。

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《Infection and immunity》 |1984年第3期|共4页
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J Z Montgomerie; A Bindereif; J B Neilands; G M Kalmanson; L B Guze;
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中图分类医学免疫学;
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1. Iron, siderophores, and the pursuit of virulence: independence of the aerobactin and enterochelin iron uptake systems in Escherichia coli. [J] . P H Williams, N H Carbonetti Infection and immunity . 1986,第3期

机译：铁，铁载体和对毒力的追求：大肠杆菌中气杆菌素和肠螯合剂铁吸收系统的独立性。
2. Aerobactin and other virulence factor genes among strains of Escherichia coli causing urosepsis: association with patient characteristics. [J] . J R Johnson, S L Moseley, P L Roberts, Infection and immunity . 1988,第2期

机译：引起尿毒症的大肠杆菌菌株中的气杆菌素和其他毒力因子基因：与患者特征有关。
3. Mixed catechol-hydroxamate and catechol-(o-hydroxy)phenacyl siderophores: synthesis and uptake studies with receptor-deficient Escherichia coli mutants [J] . Schobert R, Stangl A, Hannernann K Tetrahedron . 2008,第8期

机译：混合邻苯二酚-异羟肟酸酯和邻苯二酚-（邻-羟基）苯甲酰基铁载体：缺乏受体的大肠杆菌突变体的合成和吸收研究
4. Siderophore Receptor and Porin Protein Technology for Control of Salmonella and Escherichia coli 0157:H7 in Cattle [C] . E.T. Stevens, D.U. Thomson Annual Conference of American Association of Bovine Practitioners . 2005

机译：西参受体和孔素蛋白质技术控制沙门氏菌和大肠杆菌0157：H7在牛中
5. Interactions between energy transducer TonB and ferric hydroxamate transport proteins from Escherichia coli [D] . Carter, David M. 2010

机译：能量换能器TonB与大肠杆菌中异羟肟酸铁转运蛋白之间的相互作用
6. Association of hydroxamate siderophore (aerobactin) with Escherichia coli isolated from patients with bacteremia. [O] . J Z Montgomerie, A Bindereif, J B Neilands, 1984

机译：异羟肟酸铁载体（气杆菌素）与从菌血症患者分离的大肠杆菌的关联。
7. Association of hydroxamate siderophore (aerobactin) with Escherichia coli isolated from patients with bacteremia [O] . J Z Montgomerie, A Bindereif, J B Neilands, 1984

机译：羟肟酸盐（Aerobactin）与菌株患者患者菌大肠杆菌的结合

Association of hydroxamate siderophore (aerobactin) with Escherichia coli isolated from patients with bacteremia.

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