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Specific immune response in the human respiratory tract following oral immunization with live typhoid vaccine.

机译:活伤寒疫苗口服免疫后在人呼吸道中的特异性免疫反应。

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Specific antibody responses in the lower respiratory tract of human subjects to orally administered Salmonella typhi Ty21a are reported. These responses, predominantly of the immunoglobulin G class, were determined to be a transudate from serum. These results were supported by the similarity in responses to parenteral administration of heat-killed typhoid vaccine. Specific immunoglobulin A antibody was a poor contributor to the respiratory antibody response to either vaccine.
机译:据报道,在人类受试者的下呼吸道中,口服伤寒沙门氏菌Ty21a具有特异性抗体应答。这些反应,主要是免疫球蛋白G类,被确定为来自血清的渗出液。这些结果得到了热灭鼠伤寒疫苗胃肠外给药反应相似的支持。特异性免疫球蛋白A抗体对两种疫苗的呼吸道抗体反应均贡献不大。

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