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Lack of allelic polymorphism for the major outer membrane protein gene of the agent of guinea pig inclusion conjunctivitis (Chlamydia psittaci).

机译:豚鼠包膜结膜炎(衣原体衣原体)的主要外膜蛋白基因缺乏等位基因多态性。

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The major outer membrane protein gene (omp1) was sequenced for each of six Chlamydia psittaci (guinea pig inclusion conjunctivitis [GPIC]) strains isolated from guinea pigs. Five of the isolates were obtained in the United States during the 1960s and 1970s, including the prototype strain isolated by Murray in 1962. The other isolate was obtained from a guinea pig in England. The nucleotide sequence of the omp1 gene for each strain was identical. The lack of omp1 allelic polymorphism among GPIC isolates suggests that, unlike C. trachomatis, the GPIC agent lacks antigenic variation in the major outer membrane protein.
机译:从豚鼠分离的六个鹦鹉热衣原体(豚鼠包涵结膜炎[GPIC])菌株中的每一个,均对主要外膜蛋白基因(omp1)进行了测序。其中有5种分离株是在1960年代和1970年代在美国获得的,包括Murray于1962年分离的原型菌株。另一种分离株是从英格兰的豚鼠获得的。每个菌株的omp1基因的核苷酸序列是相同的。 GPIC分离株之间缺乏omp1等位基因多态性表明,与沙眼衣原体不同,GPIC药物在主要外膜蛋白中缺乏抗原变异。

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