Superantigen Immune Stimulation Evokes Epithelial Monocyte Chemoattractant Protein 1 and RANTES Production

Sean Jedrzkiewicz; Galina Kataeva; Cory M. Hogaboam; Steven L. Kunkel; Robert M. Strieter; Derek M. McKay

首页> 外文期刊>Infection and immunity >Superantigen Immune Stimulation Evokes Epithelial Monocyte Chemoattractant Protein 1 and RANTES Production

【24h】

Superantigen Immune Stimulation Evokes Epithelial Monocyte Chemoattractant Protein 1 and RANTES Production

机译：超抗原免疫刺激引起上皮单核细胞趋化蛋白1和RANTES产生。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Bacterial superantigens (SAgs) have been implicated in inflammatory disease, and SAg-treated mice have increased jejunal T cells. Here we show that T84 cells (a human epithelial cell line) display increased MCP-1 and RANTES mRNA expression and protein production in response to conditioned medium from Staphylococcus aureus enterotoxin B (SEB; a model SAg)-activated immune cells. Also, MCP-1 and RANTES mRNAs were increased in jejunal enterocytes isolated from SEB-treated mice. We suggest that T-cell recruitment to the gut following SAg immune activation could be partially due to epithelium-derived chemokines.

机译：细菌超抗原（SAgs）与炎性疾病有关，经SAg处理的小鼠空肠T细胞增多。在这里，我们显示T84细胞（一种人类上皮细胞系）显示出对金黄色葡萄球菌肠毒素B（SEB;模型SAg）-的条件培养基响应的MCP-1和RANTES mRNA表达和蛋白质产生的增加。激活的免疫细胞。此外，从SEB治疗的小鼠分离的空肠肠上皮细胞中的MCP-1和RANTES mRNA均增加。我们建议SAg免疫激活后T细胞募集到肠道可能部分归因于上皮衍生的趋化因子。

著录项

来源
《Infection and immunity》 |1999年第11期|共5页
作者
Sean Jedrzkiewicz; Galina Kataeva; Cory M. Hogaboam; Steven L. Kunkel; Robert M. Strieter; Derek M. McKay;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类医学免疫学;
关键词

相似文献

外文文献
中文文献
专利

1. The new antirheumatic drug KE-298 suppresses monocyte chemoattractant protein (MCP)-1 and RANTES production in rats with adjuvant-induced arthritis and in IL-1beta-stimulated synoviocytes of patients with rheumatoid arthritis. [J] . Inoue T, Yamashita M, Higaki M Rheumatology international. . 2001,第4期

机译：新的抗风湿药KE-298抑制佐剂诱导的关节炎大鼠和类风湿性关节炎患者经IL-1β刺激的滑膜细胞中单核细胞趋化蛋白（MCP）-1和RANTES的产生。
2. The new antirheumatic drug KE-298 suppresses monocyte chemoattractant protein (MCP)-1 and RANTES production in rats with adjuvant-induced arthritis and in IL-1β-stimulated synoviocytes of patients with rheumatoid arthritis [J] . Tomoyuki Inoue, Miyuki Yamashita, Megumu Higaki Rheumatology International . 2001,第4期

机译：新的抗风湿药KE-298抑制佐剂性关节炎大鼠和类风湿性关节炎患者IL-1β刺激的滑膜细胞中单核细胞趋化蛋白（MCP）-1和RANTES的产生
3. Yersinia enterocolitica Invasin Protein Triggers Differential Production of Interleukin-1, Interleukin-8, Monocyte Chemoattractant Protein 1, Granulocyte-Macrophage Colony-Stimulating Factor, and Tumor Necrosis Factor Alpha in Epithelial Cells: Implications for Understanding the Early Cytokine Network inYersinia Infections [J] . Daniel Kampik, Ralf Schulte, Ingo B. Autenrieth Infection and immunity . 2000,第5期

机译：小肠结肠炎耶尔森氏菌侵袭素蛋白触发上皮细胞中白细胞介素-1，白细胞介素8，单核细胞趋化蛋白1，粒细胞-巨噬细胞集落刺激因子和肿瘤坏死因子α的差异产生：对了解早期感染细胞中的细胞因子网络的意义。
4. Inhibition of Serine-Threonine Protein Phosphatases in Monocyte Chemoattractant Protein-1 Expression in Helicobacter pylori-Stimulated Gastric Epithelial Cells [C] . HAE-YUN CHUNG, BORAM CHA, HYEYOUNG KIM Meeting on Cell Signaling World: Signal Transduction Pathways as Therapeutic Targets . 2007

机译：幽门螺杆菌刺激的胃上皮细胞单核细胞趋化蛋白-1表达中丝氨酸-苏氨酸蛋白磷酸酶的抑制。
5. The effect of monocyte chemoattractant protein-1 concentration gradients on monocyte migration in a three-dimensional in vitro vascular tissue model. [D] . Ghousifam, Neda. 2015

机译：在三维体外血管组织模型中单核细胞趋化蛋白1浓度梯度对单核细胞迁移的影响。
6. Note: Superantigen Immune Stimulation Evokes Epithelial Monocyte Chemoattractant Protein 1 and RANTES Production [O] . Sean Jedrzkiewicz, Galina Kataeva, Cory M. Hogaboam, 1999

机译：注意：超抗原免疫刺激引起上皮单核细胞趋化蛋白1和RANTES产生
7. Yersinia enterocolitica Invasin Protein Triggers Differential Production of Interleukin-1, Interleukin-8, Monocyte Chemoattractant Protein 1, Granulocyte-Macrophage Colony-Stimulating Factor, and Tumor Necrosis Factor Alpha in Epithelial Cells: Implications for Understanding the Early Cytokine Network in Yersinia Infections [O] . Kampik, Daniel, Schulte, Ralf, Autenrieth, Ingo B. 2000

机译：小肠结肠炎耶尔森氏菌侵袭素蛋白触发上皮细胞中白细胞介素-1，白细胞介素8，单核细胞趋化蛋白1，粒细胞-巨噬细胞集落刺激因子和肿瘤坏死因子α的差异产生：理解耶尔森氏菌感染中早期细胞因子网络的意义。

Superantigen Immune Stimulation Evokes Epithelial Monocyte Chemoattractant Protein 1 and RANTES Production

摘要

著录项

相似文献

相关主题

期刊订阅