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Cl? Secretion in Colonic Epithelial Cells Induced by the Vibrio parahaemolyticus Hemolytic Toxin Related to Thermostable Direct Hemolysin

机译:Cl吗副溶血性弧菌溶血毒素诱导的结肠上皮细胞分泌与热稳定的直接溶血素有关

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摘要

A hemolytic toxin related to thermostable direct hemolysin (TDH), TDH-related hemolysin (TRH), produced by Kanagawa-phenomenon-negative Vibrio parahaemolyticus is suspected of playing an important, but yet-to-be-elucidated role in diarrhea caused by this organism. In cultured human colonic epithelial cells, TRH increases Cl? secretion, followed by elevation of intracellular calcium.
机译:神奈川现象副溶血弧菌产生的与热稳定的直接溶血素(TDH),TDH相关的溶血素(TRH)有关的溶血毒素被怀疑在发挥重要作用,但尚待解决阐明了这种生物引起的腹泻作用。在培养的人结肠上皮细胞中,TRH增加Cl ?的分泌,然后升高细胞内钙。

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