Molecular and Genomic Analysis of Genes Encoding Surface-Anchored Proteins from Clostridium difficile

Tuomo Karjalainen; Anne-Judith Waligora-Dupriet; Marina Cerquetti; Patrizia Spigaglia; Andrea Maggioni; Pierluigi Mauri

首页> 外文期刊>Infection and immunity >Molecular and Genomic Analysis of Genes Encoding Surface-Anchored Proteins from Clostridium difficile

【24h】

Molecular and Genomic Analysis of Genes Encoding Surface-Anchored Proteins from Clostridium difficile

机译：艰难梭菌表面锚定蛋白编码基因的分子和基因组分析

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The gene slpA, encoding the S-layer precursor protein in the virulent Clostridium difficile strains C253 and 79–685, was identified. The precursor protein carries a C-terminal highly conserved anchoring domain, similar to the one found in the Cwp66 adhesin (previously characterized in strain 79–685), an SLH domain, and a variable N-terminal domain mediating cell adherence. The genes encoding the S-layer precursor proteins and the Cwp66 adhesin are present in a genetic locus carrying 17 open reading frames, 11 of which encode a similar two-domain architecture, likely to include surface-anchored proteins.

机译：鉴定出了强毒的艰难梭菌菌株C253和79–685中编码S层前体蛋白的基因 slpA 。前体蛋白带有一个C端高度保守的锚定域，类似于Cwp66粘附素（以前在79-685号菌株中表征），一个SLH域和一个可变的N端域介导细胞粘附。编码S层前体蛋白和Cwp66粘附素的基因存在于带有17个开放阅读框的遗传位点中，其中11个编码相似的两结构域结构，可能包括表面锚定蛋白。 展开▼

著录项

来源
《Infection and immunity》 |2001年第5期|共5页

作者
Tuomo Karjalainen; Anne-Judith Waligora-Dupriet; Marina Cerquetti; Patrizia Spigaglia; Andrea Maggioni; Pierluigi Mauri;
展开▼

作者单位

展开▼

收录信息

原文格式 PDF

正文语种

中图分类医学免疫学;

关键词

相似文献

外文文献

中文文献

专利

1. Molecular and Genomic Analysis of Genes Encoding Surface-Anchored Proteins from Clostridium difficile [J] . Tuomo Karjalainen, Anne-Judith Waligora-Dupriet, Marina Cerquetti, Infection and immunity . 2001,第5期

机译：艰难梭菌表面锚定蛋白编码基因的分子和基因组分析

2. Transcription and Analysis of Polymorphism in a Cluster of Genes Encoding Surface-Associated Proteins of Clostridium difficile [J] . Marie-Pierre Savariau-Lacomme, Carole Lebarbier, Tuomo Karjalainen, Journal of bacteriology . 2003,第15期

机译：编码艰难梭菌表面相关蛋白的基因簇中的转录和多态性分析

3. Clostridium difficile infection rates and spectrum of disease among peripartum women at one hospital from 2003 to 2007 with molecular typing analysis of recovered Clostridium difficile isolates. [J] . Venugopal AA, Gerding DN, Johnson S American Journal of Infection Control . 2011,第3期

机译：通过对回收的艰难梭菌分离物进行分子分型分析，从2003年至2007年在一家医院的围产期妇女中艰难梭菌的感染率和疾病谱。

4. Molecular analysis of the duck plague virus US10 gene and its encoding protein [C] . Lai Maoyin, Cheng Anchun, Wang Mingshu, BMEI 2012;International Conference on Biomedical Engineering and Informatics . 2012

机译：鸭瘟US10基因及其编码蛋白的分子分析

5. Characterization of chitinase activities, and cloning, analysis, and expression of genes encoding pathogenesis-related proteins in strawberry. [D] . Khan, Anwar Ahmad. 2002

机译：草莓中几丁质酶活性的表征，编码，致病相关蛋白的基因的克隆，分析和表达。

6. Note: Molecular and Genomic Analysis of Genes Encoding Surface-Anchored Proteins from Clostridium difficile [O] . Tuomo Karjalainen, Anne-Judith Waligora-Dupriet, Marina Cerquetti, 2001

机译：注意：编码艰难梭菌表面锚定蛋白的基因的分子和基因组分析

7. Molecular and Genomic Analysis of Genes Encoding Surface-Anchored Proteins from Clostridium difficile [O] . Karjalainen, Tuomo, Waligora-Dupriet, Anne-Judith, Cerquetti, Marina, 2001

机译：艰难梭菌表面锚定蛋白编码基因的分子和基因组分析

1. 艰难梭菌分子分型与艰难梭菌感染分级的相关性研究 [J] . 舒春晖 ,王丽倩 ,温小姿 . 浙江临床医学 . 2020,第002期

2. 艰难梭菌谷氨酸脱氢酶抗原及毒素检测试剂盒对艰难梭菌感染诊断价值的Meta分析 [J] . 祁琪 ,茅一萍 ,李阳 . 中国感染控制杂志 . 2019,第006期

3. 艰难梭菌毒素基因检测及分子流行病学分析 [J] . 李洋 ,姚立琼 ,刘志武 . 临床检验杂志 . 2020,第006期

4. 杭州市富阳区住院腹泻患者艰难梭菌感染及菌株分子特征分析 [J] . 黄有平 ,金旭华 ,叶菊连 . 疾病监测 . 2019,第003期

5. 艰难梭菌临床分离株病原学和分子流行病学及临床特征分析 [J] . 陈伟 ,刘文恩 ,简子娟 . 中华检验医学杂志 . 2014,第011期

6. 动物源艰难梭菌分子分型及耐药性分析 [C] . 张莉娟 ,蒋红霞 . 中国畜牧兽医学会兽医药理毒理学分会第十四次学术讨论会 . 2017

7. 动物源艰难梭菌分子分型及耐药性分析 [A] . 张莉娟 . 2017

1. 检测和分析艰难梭菌菌株的组合物和试剂盒及用该组合物和试剂盒检测艰难梭菌菌株的方法 [P] . 中国专利： CN103484532A . 2014-01-01

2. 一种艰难梭菌毒素A/B的融合蛋白及其编码基因与应用 [P] . 中国专利： CN103772509B . 2017.01.11

3. Fusion protein Fusion protein The soluble composition of the host cell material Process to generate a neutralizing anti-toxin directed against Clostridium botulinum toxin type A antibody to purify a recombinant fusion protein derived from a Clostridium botulinum toxin type A process to generate an antitoxin neutralizing directed against clostridium difficile toxin type b antibody treatment process process to generate a neutralizing antitoxin directed against clostridium difficile type a toxin composition process to vaccinate an individual to produce neutralizing antitoxin directed against clostridium difficile toxin processing the detection of clostridium antigens difficile in an ample process of purification of toxins from clostridium difficile from a culture and process of generation of a solid dosage form of a bird antitoxin directed against a protein of clostridial toxin [P] . 外国专利： BR9509903A . 1997-11-25

机译：融合蛋白融合蛋白宿主细胞材料的可溶性组成物产生针对A型肉毒梭菌毒素的中和抗毒素的过程纯化源自A型肉毒杆菌毒素的重组融合蛋白的抗体产生针对人肉毒杆菌的抗毒素的过程B型艰难梭菌毒素抗体处理工艺过程，产生针对A艰难梭菌毒素的中和抗毒素组合物，对个体进行疫苗接种，以生产针对艰难梭菌毒素的中和抗毒素，在充足的纯化纯化过程中检测艰难梭菌抗原来源于梭状芽胞杆菌毒素蛋白的鸟抗毒素固体剂型的培养物和固体剂型产生过程中的艰难梭菌毒素

4. OLIGONUCLEOTIDES RELATING TO CLOSTRIDIUM DIFFICILE GENES ENCODING TOXIN B, TOXIN A, OR BINARY TOXIN [P] . 外国专利： EP2534164A4 . 2013-09-11

机译：与编码毒素B，毒素A或二元毒素的梭状芽胞杆菌困难基因有关的寡核苷酸

5. OLIGONUCLEOTIDES RELATING TO CLOSTRIDIUM DIFFICILE GENES ENCODING TOXIN B, TOXIN A, OR BINARY TOXIN [P] . 外国专利： EP2534164A1 . 2012-12-19

机译：与编码毒素B，毒素A或二元毒素的梭状芽胞杆菌困难基因有关的寡核苷酸

相关主题

Molecular and Genomic Analysis of Genes Encoding Surface-Anchored Proteins from Clostridium difficile

摘要

著录项

相似文献

相关主题

期刊订阅