Dissociation between delayed-type hypersensitivity and resistance to pathogenic mycobacteria demonstrated by T-cell clones.

S Hussein; J Curtis; H Akuffo; J L Turk

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Dissociation between delayed-type hypersensitivity and resistance to pathogenic mycobacteria demonstrated by T-cell clones.

机译：T细胞克隆证明了迟发型超敏反应和对病原性分枝杆菌的抗性之间的分离。

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One Lyt-2+ clone and fourteen T-helper clones (Lyt-1+ L3T4+ Lyt-2-) were isolated from Mycobacterium lepraemurium-infected BALB/c and C57BL/6 mice. All the clones were tested for their ability to transfer delayed-type hypersensitivity adoptively, and six clones were tested for their ability to transfer resistance. It was found that four L3T4+ clones that transferred delayed-type hypersensitivity responses locally and one L3T4+ clone that did not had no effect on resistance. The Lyt-2+ clone transferred increased resistance locally (77% reduction in the numbers of organisms recovered from the infection site) but did not transfer delayed footpad responses.

机译：从麻风分枝杆菌感染的BALB / c和C57BL / 6小鼠中分离出一个Lyt-2 +克隆和14个T辅助克隆（Lyt-1 + L3T4 + Lyt-2-）。测试所有克隆的过继转移迟发型超敏反应的能力，测试六个克隆的抗转移能力。结果发现，有四个L3T4 +克隆在局部转移了迟发型超敏反应，而一个L3T4 +克隆对抗性没有影响。 Lyt-2 +克隆局部转移了耐药性（从感染部位恢复的生物数量减少了77％），但没有转移延迟的足垫反应。

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《Infection and immunity》 |1987年第3期|共4页
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S Hussein; J Curtis; H Akuffo; J L Turk;
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中图分类医学免疫学;
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1. Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones. [J] . Sieben S, Kawakubo Y, Masaoudi TA, The Journal of Allergy and Clinical Immunology . 2002,第6aPta1期

机译：对对苯二胺的迟发型超敏反应是由特定字母人类T细胞克隆通过两种不同的抗原识别途径介导的。
2. Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones. [J] . Sieben S, Kawakubo Y, Al Masaoudi T, The Journal of Allergy and Clinical Immunology . 2002,第6期

机译：对对苯二胺的迟发型超敏反应是由特定字母人类T细胞克隆通过两种不同的抗原识别途径介导的。
3. Genetic regulation of delayed-type hypersensitivity responses to poly(LTyr,LGlu)-poly(DLAla)--poly(LLys). II. Evidence for a T-T-cell collaboration in delayed-type hypersensitivity responses and for a T-cell defect at the efferent phase in nonresponder H-2k mice. [J] . G Strassmann, Z Eshhar, E Mozes The Journal of Experomental Medicine . 1980,第3期

机译：对聚（LTyr，LGlu）-聚（DLAla）-聚（LLys）的迟发型超敏反应的遗传调控。二。在无反应性H-2k小鼠中，迟发型超敏反应中的T-T细胞协同作用以及传出期T细胞缺陷的证据。
4. Induction of delayed-type hypersensitivity reactions to Candida albicans in pasture-based dairy cows [C] . JE McGowan, BC Hine, BA Mallard, Conference of the New Zealand Society of Animal Production and the Australian Society of Animal Production . 2014

机译：诱导基于牧场乳制奶牛的念珠菌蛋白蛋白蛋白白醛的诱导型超敏反应
5. T cell-mediated inflammation is stereotyped: Mouse delayed-type hypersensitivity reaction and mouse T cell-mediated rejection of renal allografts share common molecular mechanisms. [D] . Venner, Jeffery M. 2011

机译：T细胞介导的炎症是定型的：小鼠迟发型超敏反应和小鼠T细胞介导的肾同种异体移植排斥反应具有共同的分子机制。
6. Dissociation between delayed-type hypersensitivity and resistance to pathogenic mycobacteria demonstrated by T-cell clones. [O] . S Hussein, J Curtis, H Akuffo, 1987

机译：T细胞克隆证明了迟发型超敏反应和对病原性分枝杆菌的抗性之间的分离。
7. Isolation of a proline-rich mycobacterial protein eliciting delayed-type hypersensitivity reactions only in guinea pigs immunized with living mycobacteria. [O] . Romain, F, Augier, J, Pescher, P, 1993

机译：富含脯氨酸的分枝杆菌蛋白的分离仅在用活的分枝杆菌免疫的豚鼠中引起延迟型超敏反应。

Dissociation between delayed-type hypersensitivity and resistance to pathogenic mycobacteria demonstrated by T-cell clones.

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