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首页> 外文期刊>Infection and immunity >Cytotoxicity of Shiga toxin for primary cultures of human colonic and ileal epithelial cells.
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Cytotoxicity of Shiga toxin for primary cultures of human colonic and ileal epithelial cells.

机译:志贺毒素对人结肠和回肠上皮细胞原代培养的细胞毒性。

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摘要

Shiga toxin purified from Shigella dysenteriae 1 was cytotoxic to cultured epithelial cells from human colon and ileum. The cytotoxicity, which affected only about 50% of treated cells, was neutralized by rabbit antiserum monospecific for Shiga toxin and mediated by protein synthesis inhibition.
机译:从痢疾志贺氏菌1纯化的志贺毒素对从人结肠和回肠培养的上皮细胞具有细胞毒性。仅对志贺毒素单特异性的兔抗血清中和了仅影响约50%处理细胞的细胞毒性,并由蛋白质合成抑制介导。

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