Continuous B-cell epitopes in Chlamydia trachomatis heat shock protein 60.

Y Yi; G Zhong; R C Brunham

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Continuous B-cell epitopes in Chlamydia trachomatis heat shock protein 60.

机译：沙眼衣原体热休克蛋白60中的连续B细胞表位。

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B-cell peptide epitopes in chlamydial heat shock protein 60 (hsp60) were elucidated with antisera from 13 rabbits immunized with Chlamydia trachomatis serovars B, C, and L2 and antisera from eight women with C. trachomatis-associated ectopic pregnancies. Thirteen major epitopes were identified with the human sera, 10 of which were also observed with rabbit antisera. Seven of the 13 epitopes recognized by human antisera exhibited cross-reactive antibody binding to homologous peptide sequences in human hsp60. Self-reactive B-cell immunity to hsp60 may contribute to chlamydial disease pathogenesis.

机译：沙眼衣原体热休克蛋白60（hsp60）中的B细胞肽表位用来自沙眼衣原体血清B，C和L2免疫的13只兔子的抗血清和来自八名沙眼衣原体相关异位妊娠妇女的抗血清进行了阐明。鉴定出人血清中有13种主要表位，其中兔抗血清中也观察到了10种。人抗血清识别的13个表位中有7个表现出与人hsp60中同源肽序列结合的交叉反应抗体。对hsp60的自我反应性B细胞免疫可能有助于衣原体疾病的发病机理。

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《Infection and immunity》 |1993年第3期|共4页
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Y Yi; G Zhong; R C Brunham;
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中图分类医学免疫学;
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1. Continuous B-cell epitopes in Chlamydia trachomatis heat shock protein 60. [J] . Y Yi, G Zhong, R C Brunham Infection and immunity . 1993,第3期

机译：沙眼衣原体热休克蛋白60中的连续B细胞表位。
2. Circulating Antibodies to a Conserved Epitope of the Chlamydia Trachomatis 60-kDa Heat Shock Protein is Associated with Decreased Spontaneous Fertility Rate in Ectopic Pregnant Women Treated by Salpingectomy. [J] . Sziller I, Fedorcsak P, Csapo Z, AJRI: American Journal of Reproductive Immunology . 2008,第2期

机译：沙眼衣原体60 kDa热休克蛋白的保守表位的循环抗体与输卵管切除术治疗的异位孕妇的自然受精率降低相关。
3. Identification of immunodominant linear B-cell epitopes within the major outer membrane protein of Chlamydia trachomatis [J] . Lifang Zhang Acta Biochimica et Biophysica Sinica . 2010,第11期

机译：沙眼衣原体主要外膜蛋白内免疫显性线性B细胞表位的鉴定
4. Study on the Anti-tumor Mechanisms of Heat Shock Protein 72/alpha-fetoprotein Epitope Peptide Complex Against Hepatocellular Carcinoma Cell Hepal-6 [C] . Bing Xu, Xiaoping Wang, Huanping Lin International Symposium on Application of Materials Science and Energy Materials . 2019

机译：热休克蛋白72 /α-胎儿表位肽复合物对肝细胞癌细胞肝癌的抗肿瘤机制研究
5. Negative regulation of heat shock genes by the HrcA repressor protein in Chlamydia trachomatis. [D] . Wilson, Adam Christopher. 2005

机译：沙眼衣原体中HrcA阻遏蛋白对热休克基因的负调控。
6. Continuous B-cell epitopes in Chlamydia trachomatis heat shock protein 60. [O] . Y Yi, G Zhong, R C Brunham 1993

机译：沙眼衣原体热休克蛋白60中的连续B细胞表位。
7. Continuous B-cell epitopes in Chlamydia trachomatis heat shock protein 60 [O] . Y Yi, G Zhong, R C Brunham 1993

机译：Chlamydia Trachomatis热休克蛋白60的连续B细胞表位

Continuous B-cell epitopes in Chlamydia trachomatis heat shock protein 60.

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