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SKN7 of Candida albicans: Mutant Construction and Phenotype Analysis

机译:白色念珠菌SKN7:突变体构建和表型分析

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The SKN7 two-component response regulator gene of Candida albicans was deleted, and the phenotype of the mutant was established. This mutant exhibited impaired growth on Spider agar and 10% serum agar compared to wild-type and gene-reconstituted strains. The skn7 mutant was sensitive to H2O2 in vitro, but its virulence was only mildly attenuated. A comparison of the Skn7p and Ssk1p response regulators of C. albicans is discussed.
机译:删除了白色念珠菌 SKN7 两组分应答调节基因,并建立了该突变体的表型。与野生型和基因重组菌株相比,该突变体在蜘蛛琼脂和10%血清琼脂上表现出受损的生长。 skn7 突变体在体外对H 2 O 2 敏感,但其毒力仅被轻度减弱。比较 C的Skn7p和Ssk1p响应调节器。讨论了白色的

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