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The hbhA Gene of Mycobacterium tuberculosis Is Specifically Upregulated in the Lungs but Not in the Spleens of Aerogenically Infected Mice

机译:结核分枝杆菌的hbhA基因在肺中特异性上调,但在气源性感染小鼠的脾脏中没有上调

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We report that hbhA is differentially regulated during Mycobacterium tuberculosis infection. Upregulation was observed in epithelial cell infection but not in macrophage infection and in the lungs but not in the spleens of infected mice, and it was greater during the early steps of infection, when bacilli disseminate from the site of primary infection.
机译:我们报道 hbhA 结核分枝杆菌感染过程中受到差异调节。在上皮细胞感染中观察到上调,但在巨噬细胞感染中和肺中未见上调,但在被感染小鼠的脾脏中未见上调,并且在感染的早期阶段,当细菌从原发感染位点传播时,上调更为明显。

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