CpG Oligodeoxynucleotides Increase the Susceptibility of Normal Mice to Infection by Candida albicans

Shuichi Ito; Joao Pedras-Vasconcelos; Dennis M. Klinman

首页> 外文期刊>Infection and immunity >CpG Oligodeoxynucleotides Increase the Susceptibility of Normal Mice to Infection by Candida albicans

【24h】

CpG Oligodeoxynucleotides Increase the Susceptibility of Normal Mice to Infection by Candida albicans

机译：CpG寡脱氧核苷酸增加正常小鼠对白色念珠菌感染的易感性

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Synthetic oligodeoxynucleotides containing CpG motifs trigger an innate immune response that typically increases host resistance to infection. Yet CpG treatment reduces the resistance of normal mice to Candida albicans infection. This effect is mediated by CpG-induced interleukin-12, indicating that CpG-dependent cytokine production may have adverse consequences for the host.

机译：包含CpG基序的合成寡聚脱氧核苷酸会触发先天免疫反应，通常会增加宿主对感染的抵抗力。然而，CpG处理降低了正常小鼠对白色念珠菌感染的抵抗力。这种作用是由CpG诱导的白介素12介导的，表明CpG依赖性细胞因子的产生可能对宿主产生不利影响。

著录项

来源
《Infection and immunity》 |2005年第9期|共3页
作者
Shuichi Ito; Joao Pedras-Vasconcelos; Dennis M. Klinman;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类医学免疫学;
关键词

相似文献

外文文献
中文文献
专利

1. Increased susceptibility of complement factor B/C2 double knockout mice and mannan-binding lectin knockout mice to systemic infection with Candida albicans. [J] . Held K, Thiel S, Loos M, Molecular Immunology . 2008,第15期

机译：补体因子B / C2双敲除小鼠和甘露聚糖结合凝集素敲除小鼠对白色念珠菌全身感染的敏感性增加。
2. CpG oligodeoxynucleotides protect mice from lethal challenge with Candida albicans via a pathway involving tumor necrosis factor-alpha- dependent interleukin-12 induction [J] . Jung-Hwa Choi, Hyun-Mi Ko, Sung Jun Park FEMS immunology and medical microbiology . 2007,第5期

机译：CpG寡脱氧核苷酸通过涉及肿瘤坏死因子-α依赖性白介素12诱导的途径保护小鼠免受白色念珠菌的致命攻击
3. Bacteria‐induced susceptibility to Candida albicansCandida albicans super‐infection in mice via monocyte methyltransferase Setdb2 [J] . Chen Xiao‐Ping, Zheng Hao, Li Wen‐Ge, Cellular microbiology . 2018,第9期

机译：细菌诱导的敏感性对念珠菌蛋白质的敏感性念珠菌念珠菌通过单核细胞甲基转移酶setdb2的小鼠超级感染
4. Antimicrobial blue light therapy for Candida albicans burn infection in mice [C] . Yunsong Zhang, Yucheng Wang, Clinton K. Murray, Conference on Micro- and Nanotechnology Sensors, Systems, and Applications . 2015

机译：抗菌蓝光疗法治疗白色念珠菌感染小鼠
5. Novel Determinants That Influence Azole Susceptibility in Candida glabrata and Candida albicans [D] . Whaley, Sarah Garland. 2018

机译：影响含有唑米菌和念珠菌念珠菌和念珠菌蛋白敏感的新的决定因素
6. CpG Oligodeoxynucleotides Increase the Susceptibility of Normal Mice to Infection by Candida albicans [O] . Shuichi Ito, Joao Pedras-Vasconcelos, Dennis M. Klinman 2005

机译：CpG寡脱氧核苷酸增加正常小鼠对白色念珠菌感染的易感性
7. CpG Oligodeoxynucleotides Increase the Susceptibility of Normal Mice to Infection by Candida albicans [O] . Ito, Shuichi, Pedras-Vasconcelos, Joao, Klinman, Dennis M. 2005

机译：CpG寡脱氧核苷酸增加正常小鼠对白色念珠菌感染的易感性
8. Effect of Local Ultraviolet Irradiation on Infections of Mice with 'Candida albicans', 'Mycobacterium bovis BCG', and 'Schistosoma mansoni' [R] . Jeevan, A., Evans, R., Brown, E. L., 1992

机译：局部紫外线照射对'白色念珠菌'，'牛分枝杆菌BCG'和'曼氏血吸虫'小鼠感染的影响

CpG Oligodeoxynucleotides Increase the Susceptibility of Normal Mice to Infection by Candida albicans

摘要

著录项

相似文献

相关主题

期刊订阅