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Induction of Emetic Response to Staphylococcal Enterotoxins in the House Musk Shrew (Suncus murinus)

机译:诱导对室内麝Sh(Suncus murinus)的葡萄球菌肠毒素的催吐反应

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摘要

The emetic responses induced by staphylococcal enterotoxin A (SEA), SEB, SEC2, SED, SEE, SEG, SEH, and SEI in the house musk shrew (Suncus murinus) were investigated. SEA, SEE, and SEI showed higher emetic activity in the house musk shrew than the other SEs. SEB, SEC2, SED, SEG, and SEH also induced emetic responses in this animal model but relatively high doses were required. The house musk shrew appears to be a valuable model for studying the mechanisms of emetic reactions caused by SEs.
机译:研究了葡萄球菌肠毒素A(SEA),SEB,SEC2,SED,SEE,SEG,SEH和SEI在室内麝香( Suncus murinus )中引起的催吐反应。 SEA,SEE和SEI在室内麝香showed中的催吐活性高于其他SE。 SEB,SEC2,SED,SEG和SEH在该动物模型中也引起催吐反应,但需要相对较高的剂量。室内麝香sh似乎是研究SEs引起催吐反应机制的有价值模型。

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